[HTML][HTML] The mechanisms crosstalk and therapeutic opportunities between ferroptosis and ovary diseases

Y Yao, B Wang, Y Jiang, H Guo, Y Li - Frontiers in Endocrinology, 2023 - frontiersin.org
Ferroptosis, a form of regulated cell death, was first defined in 2012. Ferroptosis mainly
involves iron-driven lipid peroxidation damage of cells. This process is regulated by iron …

[HTML][HTML] Alternative treatment of polycystic ovary syndrome: pre-clinical and clinical basis for using plant-based drugs

S Malik, S Saeed, A Saleem, MI Khan… - Frontiers in …, 2024 - frontiersin.org
The most common cause of infertility and metabolic problems among women of reproductive
age is polycystic ovary syndrome (PCOS), a multifaceted disorder. It is an endocrine …

Antiobesity Effect of Lactiplantibacillus plantarum Fermented Barley Extracts via the Interactions with Gut Microbiota of the Obese Adult Humans

R Pan, J Yuan, J Bai, J Zhang, J Zhang… - Journal of Food …, 2023 - Wiley Online Library
Extracts of fermented barley with Lactiplantibacillus plantarumdy‐1 (LFBE) have been
reported to exert antiobesity activity in vivo and in vitro. However, whether it worked in …

Dietary selenomethionine reduced oxidative stress by resisting METTL3-mediated m6A methylation level of Nrf2 to ameliorate LPS-induced liver necroptosis in laying …

S Li, Y Wang, A Xu, B Zhao, Y Xia, Y He, H Xue… - The Journal of Nutritional …, 2024 - Elsevier
Selenomethionine (SeMet) as the main form of daily dietary selenium, occupies essential
roles in providing antioxidant and anti-inflammatory properties, which alleviates …

The Role of N6-methyladenosine Modification in Gametogenesis and Embryogenesis: Impact on Fertility

Y Wang, C Yang, H Sun, H Jiang… - Genomics …, 2024 - academic.oup.com
The most common epigenetic modification of messenger ribonucleic acids (mRNAs) is N 6-
methyladenosine (m6A), which is mainly located near the 3'untranslated region of mRNAs …

[HTML][HTML] Polycystic ovary syndrome pathophysiology: integrating systemic, CNS and circadian processes

G Anderson - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
The conceptualization of polycystic ovary syndrome (PCOS) has primarily focused on
hormonal alterations driven by changes within the hypothalamus and ovarian granulosa …

[HTML][HTML] Ampelopsis japonica aqueous extract improves ovulatory dysfunction in PCOS by modulating lipid metabolism

H Zhu, Y Wu, Z Zhuang, J Xu, F Chen, Q Wang… - Biomedicine & …, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine and metabolic disorder
that is closely associated with the proliferation and apoptosis of ovarian granulosa cells …

METTL3 deficiency leads to ovarian insufficiency due to IL-1β overexpression in theca cells

M Cao, C Yuan, X Chen, G He, T Chen, J Zong… - Free Radical Biology …, 2024 - Elsevier
Premature ovarian insufficiency (POI) is a clinical syndrome characterised by a decline in
ovarian function in women before 40 years of age and is associated with oestradiol …

[HTML][HTML] Impact of High-Fat Diet on Ovarian Epigenetics: Insights from Altered Intestinal Butyric Acid Levels

J Qi, C Xia, Y Zhang, R Ding, Y Zhang, W Cao, C Duan… - Heliyon, 2024 - cell.com
Objective To investigate the effects of a high-fat diet (HFD) on the gut bacterium Roseburia
intestinalis and butyric acid levels, and to assess their impact on ovarian function and …

Evaluating the therapeutic potential of moxibustion on polycystic ovary syndrome: a rat model study on gut microbiota and metabolite interaction

Y Lin, H Zeng, J Lin, Y Peng, X Que, L Wang… - Frontiers in Cellular …, 2024 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a common systemic disorder related to endocrine
disorders, affecting the fertility of women of childbearing age. It is associated with glucose …