[HTML][HTML] Organ-specific endothelial cell differentiation and impact of microenvironmental cues on endothelial heterogeneity

L Gifre-Renom, M Daems, A Luttun… - International journal of …, 2022 - mdpi.com
Endothelial cells throughout the body are heterogeneous, and this is tightly linked to the
specific functions of organs and tissues. Heterogeneity is already determined from …

Physiological Barriers and Strategies of Lipid‐Based Nanoparticles for Nucleic Acid Drug Delivery

M Hu, X Li, Z You, R Cai, C Chen - Advanced Materials, 2023 - Wiley Online Library
Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …

[HTML][HTML] Mathematical models of developmental vascular remodelling: A review

JR Crawshaw, JA Flegg, MO Bernabeu… - PLoS Computational …, 2023 - journals.plos.org
Over the past 40 years, there has been a strong focus on the development of mathematical
models of angiogenesis, while developmental remodelling has received little such attention …

[PDF][PDF] The protective roles of citrus flavonoids, naringenin, and naringin on endothelial cell dysfunction in diseases

JA Adetunji, KD Fasae, AI Awe, OK Paimo… - Heliyon, 2023 - cell.com
The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …

[HTML][HTML] The role of PLVAP in endothelial cells

L Denzer, W Muranyi, H Schroten, C Schwerk - Cell and Tissue Research, 2023 - Springer
Endothelial cells play a major part in the regulation of vascular permeability and
angiogenesis. According to their duty to fit the needs of the underlying tissue, endothelial …

Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the …

SP Meda Venkata, H Li, L Xu, JY Koh… - Proceedings of the …, 2023 - National Acad Sciences
Impaired endothelial cell (EC)–mediated angiogenesis contributes to critical limb ischemia
in diabetic patients. The sonic hedgehog (SHH) pathway participates in angiogenesis but is …

Bioactive components and molecular mechanisms of Salvia miltiorrhiza Bunge in promoting blood circulation to remove blood stasis

B Wei, C Sun, H Wan, Q Shou, B Han, M Sheng… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Salvia miltiorrhiza Bunge (SM) is an outstanding
herbal medicine with various traditional effects, especially promoting blood circulation to …

Endothelium and subendothelial matrix mechanics modulate cancer cell transendothelial migration

Y Javanmardi, A Agrawal, A Malandrino… - Advanced …, 2023 - Wiley Online Library
Cancer cell extravasation, a key step in the metastatic cascade, involves cancer cell arrest
on the endothelium, transendothelial migration (TEM), followed by the invasion into the …

[HTML][HTML] Oral health as a modifiable risk factor for cardiovascular diseases

S Altamura, R Del Pinto, D Pietropaoli… - Trends in Cardiovascular …, 2023 - Elsevier
Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality worldwide
with a high socioeconomic burden. Increasing evidence supports a convincing connection …

[HTML][HTML] The impact of periodontitis on vascular endothelial dysfunction

Q Li, X Ouyang, J Lin - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
Periodontitis, an oral inflammatory disease, originates from periodontal microbiota dysbiosis
which is associated with the dysregulation of host immunoinflammatory response. This …