Endothelial cells (ECs) that line vascular and lymphatic vessels are being increasingly
recognized as important to organ function in health and disease. ECs participate not only in …

Diabetic cardiomyopathy (DCM) is a serious complication of diabetes mellitus (DM).
However, the precise molecular mechanisms remain largely unclear, and it is still a …

Microbubbles (MB) are widely used for ultrasound (US) imaging and drug delivery. MB are
typically spherically shaped, due to surface tension. When heated above their glass …

Reduced blood flow velocity in the vein triggers inflammation and is associated with the
release into the extracellular space of alarmins or damage-associated molecular patterns …

Epidemiological studies suggest that the severity of periodontitis is higher in people with
diabetes than in healthy individuals. Insulin resistance might play a crucial role in the …

Tumour progression and metastasis remain the leading causes of cancer-related death
worldwide. Tumour angiogenesis is essential for tumour progression. The vasculature …

Liver fibrosis is a process of over‐extracellular matrix (ECM) aggregation and angiogenesis,
which develops into cirrhosis and hepatocellular carcinoma (HCC). With the increasing …

The tumor microenvironment is a highly complex and dynamic mixture of cell types,
including tumor, immune and endothelial cells (ECs), soluble factors (cytokines …

Sex-specific differences in biology and physiology likely start at the time of conception and
progress and mature during the pre-puberty time frame and then during the transitions …

Vascular endothelial injury in diabetes mellitus (DM) is the major cause of vascular disease,
which is closely related to the occurrence and development of a series of vascular …