Neurotrophins are a family of proteins that regulate neuronal survival, synaptic function, and
neurotransmitter release, and elicit the plasticity and growth of axons within the adult central …

Since its discovery, nerve growth factor (NGF) has long occupied a critical role in
developmental and adult neurobiology for its many important regulatory functions on the …

This review provides a comprehensive analysis of the structure, neurochemical content, and
functions of corneal nerves, with special emphasis on human corneal nerves. A revised …

Brain-derived neurotrophic factor (BDNF), a member of the nerve growth factor (NGF) gene
family, has been shown to influence the survival and differentiation of specific classes of …

There is increasing evidence that neurotrophins (NTs) are involved in processes of neuronal
plasticity besides their well-established actions in regulating the survival, differentiation, and …

Neurons are specialized cells with a complex morphology that represent the functional unit
of the nervous system. They are generated in remarkable numbers, particularly in higher …

Adult-derived hippocampal progenitors generate neurons, astrocytes, and
oligodendrocytesin vitroand following grafting into the adult brain. Although these …

The role of neurotrophic factors in the maintenance and survival of peripheral neuronal cells
has been the subject of numerous studies. Administration of exogenous neurotrophic factors …

Over the past 20 years, genetic studies have illuminated critical pathways in the
hypothalamus and brainstem mediating energy homeostasis, such as the melanocortin …

The signaling mechanisms that control the survival of CNS neurons are poorly understood.
Here we show that, in contrast to PNS neurons, the survival of purified postnatal rat retinal …