Growth hormone in fertility and infertility: Mechanisms of action and clinical applications

CW Chang, YW Sung, YW Hsueh, YY Chen… - Frontiers in …, 2022 - frontiersin.org
Secreted by the anterior pituitary gland, growth hormone (GH) is a peptide that plays a
critical role in regulating cell growth, development, and metabolism in multiple targeted …

Precision medicine for chronic endometritis: computer-aided diagnosis using deep learning model

M Mihara, T Yasuo, K Kitaya - Diagnostics, 2023 - mdpi.com
Chronic endometritis (CE) is a localized mucosal infectious and inflammatory disorder
marked by infiltration of CD138 (+) endometrial stromal plasmacytes (ESPC). CE is drawing …

Regulation of ovarian function by growth hormone: potential intervention of ovarian aging

L Han, H Tian, X Guo, L Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Growth hormone (GH) is mainly secreted by eosinophils of anterior pituitary gland. GH plays
an important role in regulating the growth and development of many tissues and cells, so it is …

[HTML][HTML] Antioxidants and Fertility in Women with Ovarian Ageing: a Systematic Review and Meta-Analysis

Y Shang, N Song, R He, M Wu - Advances in Nutrition, 2024 - Elsevier
Ovarian ageing is a major factor for female subfertility. Multiple antioxidants have been
applied in different clinical scenarios, but their effects on fertility in women with ovarian …

Recombinant human luteinizing hormone increases endometrial thickness in women undergoing assisted fertility treatments: a systematic review and meta-analysis

R Mao, X Hou, X Feng, R Wang, X Fei, J Zhao… - Frontiers in …, 2024 - frontiersin.org
Introduction The optimal dosage of recombinant human luteinizing hormone (r-hLH) and its
impact on endometrial thickness (EMT) when administered alongside recombinant human …

An Update on Experimental Therapeutic Strategies for Thin Endometrium

Y Tang, C Frisendahl, PG Lalitkumar… - Endocrines, 2023 - mdpi.com
Infertility caused by a thin endometrium remains a significant challenge in assisted
reproduction and is often associated with a low success rate after treatment with assisted …

Comparative efficacy of different growth hormone supplementation protocols in improving clinical outcomes in women with poor ovarian response undergoing …

Z Xu, W Tong, Z Yang, H Zhang, X Chen - Scientific Reports, 2024 - nature.com
Growth hormone (GH) has a long-standing history of use as an adjunctive therapy in the
treatment of poor ovarian response (POR), but the optimal dosage and timing remains …

Growth hormone supplementation ameliorates blastocyst euploidy rates and improves pregnancy outcomes in women undergoing preimplantation genetic testing for …

Q Guo, P Liu, W Zhou, M Xia, J Li, J Lu, JL Ma… - Frontiers in …, 2023 - frontiersin.org
Background Growth hormone (GH) supplementation has been shown to improve oocyte
quality and live birth, but few studies have examined whether GH can reduce embryonic …

Effect of growth hormone administration on ameliorating pregnancy outcome in women with advanced maternal age and exploration of its optimized utilization

Q Feng, Y Wang, H Han, H Shen - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Age-related fertility decay is a great challenge for clinicians. Growth hormone
(GH) supplementation has been studied as an adjuvant since late 1980s. However, it has …

New advances in the treatment of thin endometrium

Y Wang, Z Tang, X Teng - Frontiers in Endocrinology, 2024 - frontiersin.org
Thin endometrium (TE) is defined as a mid-luteal endometrial thickness≤ 7mm. TE can
affect endometrial tolerance, leading to lower embryo implantation rates and clinical …