Stroke is the second leading cause of death and a major cause of disability worldwide. Both
modifiable and non-modifiable risk factors can affect the occurrence of ischemic stroke at …

Background The associations of the apolipoprotein B gene (APOB) rs693 and rs17240441
polymorphisms with plasma levels of APOB and lipids have been widely explored, but the …

Background. Type 2 diabetes mellitus (T2DM) and periodontitis (P) commonly occur as
comorbidities, but the commonalities in the genetic makeup of affected individuals is largely …

Oxidatively modified low-density lipoproteins (oxLDL) play an important role in the
occurrence and progression of atherosclerosis. To identify the genetic factors influencing the …

Background The objective of this study was to evaluate whether apolipoprotein gene
polymorphisms confer susceptibility to osteonecrosis of the femoral head (ONFH). Methods …

Serum lipids are associated with myocardial infarction and cardiovascular disease in
humans. Here we dissected the genetic architecture of blood lipid traits by applying genome …

Familial hypobetalipoproteinemia (FHBL) is a codominant genetic disorder characterized by
reduced plasma levels of low-density lipoprotein cholesterol and apolipoprotein B. To our …

This study aimed to assess the association of APO gene polymorphisms and ischemic stroke
risk in a Chinese Han population. In this case-control study, we genotyped 14 single …

Myocardial infarction (MI) is when a blood clot in the coronary artery obstructs blood flow to a
specific part of the heart, leading to the death of myocardium in that area. The development …

Lipoprotein lipase is a key enzyme in lipid metabolism with reported variants associated with
obesity, hypertension, type 2 diabetes, and coronary heart disease. This study was …