During fibrosis,(myo) fibroblasts deposit large amounts of extracellular matrix proteins,
thereby replacing healthy functional tissue. In liver fibrosis, this leads to the loss of …

A notable increase in direct oral anticoagulant (DOAC) use has been observed in the last
decade. This trend has surpassed the prescription of vitamin K antagonists (VKAs) due to …

Background The clinical impact of Nonalcoholic fatty liver disease (NAFLD) in patients with
atrial fibrillation (AF) is still controversial. Aim To evaluate the 1-year risk of all-cause death …

Background and aims Major bleeding events during orthotopic liver transplantation (OLT)
are associated with poor outcomes. The proportion of this risk related to portal hypertension …

Background and aims Despite several recent international guidelines, no consensus exists
on the bleeding risk of the procedure nor on thresholds for haemostatic parameters …

Gastrointestinal hemorrhage remains one of the most common causes of morbidity and
mortality among patients with liver cirrhosis. Mostly, these patients bleed from the …

Splanchnic vein thrombosis includes Budd-Chiari syndrome and portal vein thrombosis.
These diseases share common features:(i) they are rare diseases and (ii) they can lead to …

Methods In this open label randomized controlled trial, patients with cirrhosis and abnormal
CCT who were undergoing an invasive procedure were randomized to receive blood …

Introducción. En los estadios avanzados de la cirrosis se pueden presentar coagulopatías,
las cuales se definen como los trastornos en el sistema de coagulación y se identifican por …

Splanchnic vein thrombosis (SVT) is a manifestation of venous thromboembolism in an
unusual site. Portal, mesenteric, and splenic veins are the most common vessels involved in …