Low-gradient aortic stenosis

MA Clavel, J Magne, P Pibarot - European heart journal, 2016 - academic.oup.com
An important proportion of patients with aortic stenosis (AS) have a 'low-gradient'AS, ie a
small aortic valve area (AVA< 1.0 cm2) consistent with severe AS but a low mean …

Low-flow, low-gradient aortic stenosis with normal and depressed left ventricular ejection fraction

P Pibarot, JG Dumesnil - Journal of the American College of Cardiology, 2012 - jacc.org
Low-flow, low-gradient (LF-LG) aortic stenosis (AS) may occur with depressed or preserved
left ventricular ejection fraction (LVEF), and both situations are among the most challenging …

Impact of aortic valve calcification, as measured by MDCT, on survival in patients with aortic stenosis: results of an international registry study

MA Clavel, P Pibarot, D Messika-Zeitoun… - Journal of the American …, 2014 - jacc.org
Background: Aortic valve calcification (AVC) load measures lesion severity in aortic stenosis
(AS) and is useful for diagnostic purposes. Whether AVC predicts survival after diagnosis …

The complex nature of discordant severe calcified aortic valve disease grading: new insights from combined Doppler echocardiographic and computed tomographic …

MA Clavel, D Messika-Zeitoun, P Pibarot… - Journal of the American …, 2013 - jacc.org
Objectives: With concomitant Doppler echocardiography and multidetector computed
tomography (MDCT) measuring aortic valve calcification (AVC) load, this study aimed at …

Outcome of patients with aortic stenosis, small valve area, and low-flow, low-gradient despite preserved left ventricular ejection fraction

MA Clavel, JG Dumesnil, R Capoulade… - Journal of the American …, 2012 - jacc.org
Objectives: The aim of this case match study was to compare the outcome of patients with
paradoxical low-flow (left ventricular ejection fraction [LVEF]≥ 50% but stroke volume …

Flow-gradient patterns in severe aortic stenosis with preserved ejection fraction: clinical characteristics and predictors of survival

MF Eleid, P Sorajja, HI Michelena, JF Malouf… - Circulation, 2013 - Am Heart Assoc
Background—Among patients with severe aortic stenosis (AS) and preserved ejection
fraction, those with low gradient (LG) and reduced stroke volume may have an adverse …

Outcome of patients with low-gradient “severe” aortic stenosis and preserved ejection fraction

N Jander, J Minners, I Holme, E Gerdts, K Boman… - Circulation, 2011 - Am Heart Assoc
Background—Retrospective studies have suggested that patients with a low transvalvular
gradient in the presence of an aortic valve area< 1.0 cm2 and normal ejection fraction may …

Prognostic value of follow-up hemodynamic variables after initial management in pulmonary arterial hypertension

J Weatherald, A Boucly, D Chemla, L Savale, M Peng… - Circulation, 2018 - Am Heart Assoc
Background: Hemodynamic variables such as cardiac index and right atrial pressure have
consistently been associated with survival in pulmonary arterial hypertension (PAH) at the …

Cardiac imaging for assessing low-gradient severe aortic stenosis

MA Clavel, IG Burwash, P Pibarot - JACC: Cardiovascular Imaging, 2017 - jacc.org
Up to 40% of patients with aortic stenosis (AS) harbor discordant Doppler-
echocardiographic findings, the most common of which is the presence of a small aortic …

Low-gradient aortic valve stenosis: myocardial fibrosis and its influence on function and outcome

S Herrmann, S Störk, M Niemann, V Lange… - Journal of the American …, 2011 - jacc.org
Objectives: This prospective cohort study in patients with aortic stenosis (AS) aimed to
identify surrogates of myocardial fibrosis that are easy to derive in clinical practice, allow the …