Beta-2 Adrenergic Receptor (ADRB2) Gene Polymorphisms and the Risk of Asthma: A Meta-Analysis of Case-Control Studies

SQ Liang, XL Chen, JM Deng, X Wei, C Gong… - PloS one, 2014 - journals.plos.org
Background and Objective A number of studies have assessed the relationship between
beta-2 adrenergic receptor (ADRB2) gene polymorphisms and asthma risk. However, the …

Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

LD Sun, FL Xiao, Y Li, WM Zhou, HY Tang, XF Tang… - Nature …, 2011 - nature.com
Atopic dermatitis is a chronic, relapsing form of inflammatory skin disorder that is affected by
genetic and environmental factors. We performed a genome-wide association study of …

Association of β2-adrenergic receptor gene polymorphisms (rs1042713, rs1042714, rs1042711) with asthma risk: a systematic review and updated meta-analysis

S Zhao, W Zhang, X Nie - BMC Pulmonary Medicine, 2019 - Springer
Background The published data on the association between β2-adrenergic receptor gene
polymorphisms and asthma susceptibility are inconclusive. To derive a more precise …

[HTML][HTML] Beta2-adrenergic receptor variants in children and adolescents with bronchial asthma

EA Toraih, MH Hussein, A Ibrahim… - Frontiers in Bioscience …, 2019 - imrpress.com
The region encoding the N-terminal of human β2-adrenergic receptor gene (ADRB2) shows
several polymorphisms. To this end, we studied change in susceptibility and/or response to …

Role of THRB, ARG1, and ADRB2 Genetic Variants on Bronchodilators Response in Asthmatic Children

A Scaparrotta, M Franzago… - Journal of aerosol …, 2019 - liebertpub.com
Background: An interindividual variability in response to short-acting bronchodilator drugs
(short-acting inhaled β2-agonists, SABA) exists and this is linked in part to genetic factors …

Association of CFTR gene mutation with bronchial asthma

N Maurya, S Awasthi, P Dixit - Indian Journal of Medical Research, 2012 - journals.lww.com
Mutation on both the copies of cystic fibrosis transmembrane conductance regulator (CFTR)
gene results in cystic fibrosis (CF), which is a recessively transmitted genetic disorder. It is …

Personalized medicine in children with asthma

MW Pijnenburg, S Szefler - Paediatric respiratory reviews, 2015 - Elsevier
Personalized medicine for children with asthma aims to provide a tailored management of
asthma, which leads to faster and better asthma control, has less adverse events and may …

[PDF][PDF] An association and meta-analysis study of 4 SNPs from beta-2 adrenergic receptor (ADRB2) gene with risk of asthma in children

X Guo, H Zheng, C Mao, E Guan… - Asian Pac J Allergy …, 2016 - apjai-journal.org
Objective: We performed a case-control study to investigate the association of 4 SNPs in the
ADRB2 gene with risk of asthma in children, and then conducted a meta-analysis by …

Association study of the β2-adrenergic receptor gene polymorphisms and hypertension in the Northern Han Chinese

Y Lou, J Liu, Y Li, Y Liu, Z Wang, K Liu, H Wu, Q Niu… - PloS one, 2011 - journals.plos.org
Background The β2-adrenergic receptor (ADRB2) gene has been widely researched as a
candidate gene for essential hypertension (EH), but no consensus has been reached in …

gene polymorphisms and salbutamol responsiveness in Serbian children with asthma

N Jovicic, T Babic, S Dragicevic, B Nestorovic… - Balkan Journal of …, 2018 - sciendo.com
Inhaled β2 adrenergic receptor (β2-AR) agonists are the mainstay of asthma therapy. The β2-
AR protein is encoded by the ADRB2gene and variants within this gene can have significant …