The relative potency and safety of endothelial progenitor cells and unselected mononuclear cells for recovery from myocardial infarction and ischemia

H Sekiguchi, M Ii, DW Losordo - Journal of cellular physiology, 2009 - Wiley Online Library
Endothelial progenitor cells (EPCs) are a subset of the total mononuclear cell population
(tMNCs) that possess an enhanced potential for differentiation within the endothelial‐cell …

Cell delivery routes for stem cell therapy to the heart: current and future approaches

NG Campbell, K Suzuki - Journal of cardiovascular translational research, 2012 - Springer
An important factor to determine the success of stem cell therapy to the heart is the choice of
cell delivery route. This will affect the fate of donor cells and subsequently influence the …

Bone marrow and circulating stem/progenitor cells for regenerative cardiovascular therapy

MA Alaiti, M Ishikawa, MA Costa - Translational Research, 2010 - Elsevier
Cardiovascular disease is the leading cause of death and disability in the Western world. In
addition to the advancement of current therapeutic approaches to reduce the associated …

[HTML][HTML] Intraoperative stem cell therapy

MB Coelho, JMS Cabral, JM Karp - Annual review of biomedical …, 2012 - annualreviews.org
Stem cells hold significant promise for regeneration of tissue defects and disease-modifying
therapies. Although numerous promising stem cell approaches are advancing in clinical …

Reduction in infarct size, but no functional improvement after bone marrow cell administration in a porcine model of reperfused myocardial infarction

AD Moelker, T Baks, EJ Van den Bos… - European heart …, 2006 - academic.oup.com
Aims Stem cell therapy after myocardial infarction (MI) has been studied in models of
permanent coronary occlusion. We studied the effect of intracoronary administration of …

[HTML][HTML] Cell-based therapy for heart disease: a clinically oriented perspective

P Menasche - Molecular therapy, 2009 - cell.com
Over the past decade, cell therapy has emerged as a potential new treatment of a variety of
cardiac diseases, including acute myocardial infarction, refractory angina, and chronic heart …

[HTML][HTML] Endothelial progenitor cells: what use for the cardiologist?

A Siddique, E Shantsila, GYH Lip, C Varma - Journal of angiogenesis …, 2010 - Springer
Abstract Endothelial Progenitor Cells (EPC) were first described in 1997 and have since
been the subject of numerous investigative studies exploring the potential of these cells in …

[HTML][HTML] Stem cells for neurovascular repair in stroke

K Shinozuka, T Dailey, N Tajiri, H Ishikawa… - Journal of stem cell …, 2013 - ncbi.nlm.nih.gov
Stem cells exert therapeutic effects against ischemic stroke via transplantation of exogenous
stem cells or stimulation of endogenous stem cells within the neurogenic niches of …

Cellular therapy and myocardial tissue engineering: the role of adult stem and progenitor cells

KH Wu, YL Liu, B Zhou, ZC Han - European journal of cardio …, 2006 - academic.oup.com
Acquired cardiovascular diseases and complex congenital heart diseases are leading
causes of morbidity and mortality. Cellular therapy and tissue engineering are emerging as …

Current status and future prospects for cell transplantation to prevent congestive heart failure

P Menasché - Seminars in thoracic and cardiovascular surgery, 2008 - Elsevier
Although most cardiac cell therapy trials have focused on patients with acute myocardial
infarction, attempts at “regenerating” chronically failing hearts have also been performed …