Bile acids are a large family of atypical steroids which exert their functions by binding to a
family of ubiquitous cell membrane and nuclear receptors. There are two main bile acid …

Worldwide, there is an array of clinical trials under way to evaluate treatment options against
coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome …

Pre-clinical models have shown that targeting pancreatic stellate cells with all-trans-retinoic-
acid (ATRA) reprograms pancreatic stroma to suppress pancreatic ductal adenocarcinoma …

The retinoids are a group of compounds including vitamin A and its active metabolite all-
trans-retinoic acid (ATRA). Retinoids regulate a variety of physiological functions in multiple …

Objective: This narrative review gives an overview on the essential role of adequate nutrition
to an optimally functioning immune defence. Micronutrients act as regulators of the immune …

Vitamin A (all-trans-retinol) is a fat-soluble micronutrient which together with its natural
derivatives and synthetic analogues constitutes the group of retinoids. They are involved in a …

Retinoids regulate a wide spectrum of cellular functions from the embryo throughout
adulthood, including cell differentiation, metabolic regulation, and inflammation. These traits …

Nuclear receptors (NRs) are transcription factors actively involved in many aspects of human
physiology and pathology, serving as sensors of stimuli, master regulators of downstream …

This review highlights new findings that have deepened our understanding of the
mechanisms of leukemogenesis, therapy and resistance in acute promyelocytic leukemia …

The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …