Novel catalytic antioxidant formulation decreases oxidative stress, neuroinflammation and cognitive dysfunction in a model of nerve agent intoxication

LP Liang, JN Pearson-Smith, BJ Day, M Patel - Journal of Pharmacology and …, 2024 - ASPET
Reactive oxygen species have an emerging role in the pathologic consequences of status
epilepticus. We have previously demonstrated the efficacy of a water-for-injection …

Cuproptosis-related genes signature and validation of differential expression and the potential targeting drugs in temporal lobe epilepsy

X Yang, X Zhang, K Shen, Z Wang, G Liu… - Frontiers in …, 2023 - frontiersin.org
Introduction: Temporal lobe epilepsy (TLE) is the most common subtype of epilepsy in adults
and is characterized by neuronal loss, gliosis, and sprouting mossy fibers in the …

Clinical characteristics and risk factors of cerebral cavernous malformation-related epilepsy

P Zhang, H Zhang, C Shi, J Zhou, J Dong, M Liang… - Epilepsy & Behavior, 2023 - Elsevier
Purpose This study aimed to summarize the clinical characteristics and explore the risk
factors for cerebral cavernous malformation (CCM)-related epilepsy (CRE). Methods We …

[HTML][HTML] Substantial outcome improvement using a refined pilocarpine mouse model of temporal lobe epilepsy

A Vigier, N Partouche, FJ Michel, V Crépel… - Neurobiology of …, 2021 - Elsevier
Systemic pilocarpine treatment is one of the most reliable means of inducing temporal lobe
epilepsy (TLE). However, the traditional pilocarpine injection protocol using mice was …

Bilateral glymphatic dysfunction and its association with disease duration in unilateral temporal lobe epilepsy patients with hippocampal sclerosis

F Xie, C Zhou, H Jin, W Xing, D Wang - Epilepsy & Behavior, 2024 - Elsevier
Objective In this study, the diffusion tensor imaging along perivascular space analysis (DTI-
ALPS) technique was utilized to evaluate the functional changes in the glymphatic system of …