Strategy for treatment of infected diabetic foot ulcers

M Chang, TT Nguyen - Accounts of chemical research, 2021 - ACS Publications
Conspectus Diabetic foot ulcers (DFUs) are chronic wounds that develop in 30% of diabetic
patients. In DFUs, the normal wound healing process consisting of inflammation …

Metabolic regulation of cell growth and proliferation

J Zhu, CB Thompson - Nature reviews Molecular cell biology, 2019 - nature.com
Cellular metabolism is at the foundation of all biological activities. The catabolic processes
that support cellular bioenergetics and survival have been well studied. By contrast, how …

Cellular and molecular mechanisms of skin wound healing

OA Peña, P Martin - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

Therapeutic strategies for enhancing angiogenesis in wound healing

AP Veith, K Henderson, A Spencer, AD Sligar… - Advanced drug delivery …, 2019 - Elsevier
The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing

X Zhao, H Wu, B Guo, R Dong, Y Qiu, PX Ma - Biomaterials, 2017 - Elsevier
Injectable self-healing hydrogel dressing with multifunctional properties including anti-
infection, anti-oxidative and conductivity promoting wound healing process will be highly …

[HTML][HTML] Diabetes and wound angiogenesis

UA Okonkwo, LA DiPietro - International journal of molecular sciences, 2017 - mdpi.com
Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in
sight. Complications of DM2 involve a myriad of comorbidities including the serious …

Potential applications of nanomaterials and technology for diabetic wound healing

Q Bai, K Han, K Dong, C Zheng, Y Zhang… - International journal …, 2020 - Taylor & Francis
Diabetic wound shows delayed and incomplete healing processes, which in turn exposes
patients to an environment with a high risk of infection. This article has summarized current …

[HTML][HTML] Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2

CJ Peach, VW Mignone, MA Arruda… - International journal of …, 2018 - mdpi.com
Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …

Angiogenesis and wound repair: when enough is enough

LA DiPietro - Journal of Leucocyte Biology, 2016 - academic.oup.com
All animals heal, and the ability to heal is requisite for human health. One aspect of repair
that has always been considered to be essential for adequate healing is the creation of a …

Macrophages in bone fracture healing: their essential role in endochondral ossification

C Schlundt, T El Khassawna, A Serra, A Dienelt… - Bone, 2018 - Elsevier
In fracture healing, skeletal and immune system are closely interacting through common cell
precursors and molecular mediators. It is thought that the initial inflammatory reaction, which …