Understanding the pathogenesis of neuropsychiatric disorders is a substantial challenge for
neurobiologists. It has long been hoped that identifying alleles that confer increased risk of …

Objective: Prior research has consistently documented a strong association between gen
eralized anxiety disorder (GAD) and substance use disorder (SUD). Comorbidity of GAD and …

Substance use disorders continue to impose increasing medical, financial and emotional
burdens on society in the form of morbidity and overdose, family disintegration, loss of …

The present study examined the association between alcohol use disorders (AUDs) and
psychological distress over an 11-year period using a sample of 378 young adults (46 …

Generalized anxiety disorder (GAD) has undergone a series of revisions in its diagnostic
criteria that has moved it, nosologically, away from its original affiliation with panic disorder …

Even though a variety of treatments are available for depression, many patients experience
an incomplete response, resulting in chronic functional impairment. The authors present a …

Background Polysubstance use (PSU) is associated with worse prognosis and poorer
physical and mental health compared to single substance use. The current study provides …

Importance Psychiatric conditions in parents are associated with many psychiatric and
nonpsychiatric outcomes in offspring. However, it remains unknown whether this …

Generalized anxiety disorder (GAD) and major depressive disorder (MDD) demonstrate a
strong relationship to each other at both genotypic and phenotypic levels, and both …

The authors hypothesized that anxiety and unipolar mood disorders are often comorbid
because each disorder indicates a broad, higher order factor. In a clinical subsample of the …