Modulation of cartilage's response to injury: can chondrocyte apoptosis be reversed?

I Pountos, PV Giannoudis - Injury, 2017 - Elsevier
Osteoarthritis is characterized by a chronic, progressive and irreversible degradation of the
articular cartilage associated with joint inflammation and a reparative bone response. More …

Hyaluronic acid modified curcumin-loaded chitosan nanoparticles inhibit chondrocyte apoptosis to attenuate osteoarthritis via upregulation of activator protein 1 and …

J Wang, L Zhang, J Zhu, J Gu… - Journal of Biomedical …, 2022 - ingentaconnect.com
Hyaluronic acid (HA) and curcumin (CUR) have been previously utilized for osteoarthritis
(OA) treatment. CUR-loaded chitosan nanoparticles (CUR@ CS NPs) and HA CUR@ CS …

[PDF][PDF] Herbal remedies for neurodegenerative disorder (Alzheimer's disease): A Review

P Agarwal, S Alok, A Fatima, PP Singh - International Journal of …, 2013 - Citeseer
Alzheimer's disease, a neurodegenerative disorder is characterized by intense memory loss
enough to interfere with social and occupational execution. It is the most general form of …

Oxymatrine Protects Chondrocytes against IL‐1β‐triggered Apoptosis in Vitro and Inhibits Osteoarthritis in Mice Model

D Mohetaer, L Cao, Y Wang - … ‐Based Complementary and …, 2022 - Wiley Online Library
Background. Osteoarthritis (OA) is a multifactorial disease with various risk factors, resulting
in the degeneration of articular cartilage and whole joints. However, to date, no effective …

Curcumin protects rabbit articular chondrocytes against sodium nitroprusside-induced apoptosis in vitro

P Zhao, J Cheng, J Geng, M Yang, Y Zhang… - European Journal of …, 2018 - Elsevier
The preventive and therapeutic effects of curcumin on degeneration of articular (joint)
cartilage diseases have rarely been investigated. In the present study, the protective effects …

Targeting Oxidative Stress Markers, Xanthine Oxidase, TNFRSF11A and Cathepsin L in Curcumin-Treated Collagen-Induced Arthritis: A Physiological and COSMO …

S Bisset, W Sobhi, A Attoui, T Lamaoui, YAB Jardan… - Inflammation, 2023 - Springer
The effectiveness of curcumin in preventing and treating collagen-induced inflammatory
arthritis (CIA) in rats and oxidative stress in rats was investigated. We investigated …

[HTML][HTML] Endoplasmic reticulum stress affected chondrocyte apoptosis in femoral head necrosis induced by glucocorticoid in broilers

M Zhang, S Li, K Pang, Z Zhou - Poultry science, 2019 - Elsevier
In our previous study, chondrocyte apoptosis in femoral head necrosis (FHN)-affected
broilers was found to be associated with the endoplasmic reticulum stress (ERS) signaling …

Immunomodulatory perspectives of potential biological spices with special reference to cancer and diabetes

M Imran, M Nadeem, F Saeed, A Imran… - Food and Agricultural …, 2017 - Taylor & Francis
In millennia, nutritionists are motivated to explore innovative approaches against lifestyle-
related syndromes for improving public health and life span. Spices are the promising and …

[HTML][HTML] Mechanisms and pharmaceutical action of lipid nanoformulation of natural bioactive compounds as efficient delivery systems in the therapy of osteoarthritis

O Craciunescu, M Icriverzi, PE Florian, A Roseanu… - Pharmaceutics, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative joint disease. An objective of the nanomedicine and
drug delivery systems field is to design suitable pharmaceutical nanocarriers with …

姜黄素通过调节Wnt/β-catenin 信号通路促进软骨细胞增殖的研究

马勇, 王礼宁, 郭杨, 盛旭飏, 周信, 孙福荣 - 广州中医药大学学报, 2017 - cqvip.com
[目的] 探讨姜黄素通过Wnt/β-catenin 信号通路对软骨细胞增殖的影响.[方法] 取4
周龄雌雄新西兰大白兔各1 只, 采用酶消化法构建体外软骨细胞培养体系; 应用形态学观察 …