Collagen and elastin biomaterials for the fabrication of engineered living tissues

D Miranda-Nieves, EL Chaikof - ACS Biomaterials Science & …, 2017 - ACS Publications
Collagen and elastin represent the two most predominant proteins in the body and are
responsible for modulating important biological and mechanical properties. Thus, the focus …

Elastin-based materials

JF Almine, DV Bax, SM Mithieux… - Chemical Society …, 2010 - pubs.rsc.org
Elastin is a versatile elastic protein that dominates flexible tissues capable of recoil, and
facilitates commensurate cell interactions in these tissues in all higher vertebrates. Elastin's …

Tissue engineered skin substitutes

P Goodarzi, K Falahzadeh, M Nematizadeh… - Cell Biology and …, 2018 - Springer
The fundamental skin role is to supply a supportive barrier to protect body against harmful
agents and injuries. Three layers of skin including epidermis, dermis and hypodermis form a …

Protein-based materials: from sources to innovative sustainable materials for biomedical applications

NHCS Silva, C Vilela, IM Marrucho… - Journal of Materials …, 2014 - pubs.rsc.org
Proteins display an essential role in numerous natural systems due to their structural and
biological properties. Given their unique properties, proteins have been thoroughly …

Defining and designing polymers and hydrogels for neural tissue engineering

ER Aurand, KJ Lampe, KB Bjugstad - Neuroscience research, 2012 - Elsevier
The use of biomaterials, such as hydrogels, as neural cell delivery devices is becoming
more common in areas of research such as stroke, traumatic brain injury, and spinal cord …

Electrospun synthetic human elastin: collagen composite scaffolds for dermal tissue engineering

J Rnjak-Kovacina, SG Wise, Z Li, PKM Maitz, CJ Young… - Acta biomaterialia, 2012 - Elsevier
We present an electrospun synthetic human elastin: collagen composite scaffold aimed at
dermal tissue engineering. The panel of electrospun human tropoelastin and ovine type I …

Tropoelastin: a versatile, bioactive assembly module

SG Wise, GC Yeo, MA Hiob, J Rnjak-Kovacina… - Acta biomaterialia, 2014 - Elsevier
Elastin provides structural integrity, biological cues and persistent elasticity to a range of
important tissues, including the vasculature and lungs. Its critical importance to normal …

Polymer-based hydrogel scaffolds for skin tissue engineering applications: a mini-review

KH Jeong, D Park, YC Lee - Journal of Polymer Research, 2017 - Springer
Polymer hydrogels consist of a three-dimensional (3D) structure with cross-linked networks
rich in a huge amount of water through hydrogen-bonding interactions, making them highly …

Advancements in extracellular matrix-based biomaterials and biofabrication of 3D organotypic skin models

SJ Phang, S Basak, HX Teh… - ACS biomaterials …, 2022 - ACS Publications
Over the last decades, three-dimensional (3D) organotypic skin models have received
enormous attention as alternative models to in vivo animal models and in vitro two …

Fabricated elastin

GC Yeo, B Aghaei‐Ghareh‐Bolagh… - Advanced …, 2015 - Wiley Online Library
The mechanical stability, elasticity, inherent bioactivity, and self‐assembly properties of
elastin make it a highly attractive candidate for the fabrication of versatile biomaterials. The …