Because of the compartmentalization of disciplines that shaped the academic landscape of
biology and biomedical sciences in the past, physiological systems have long been studied …

Microglia are brain‐resident macrophages forming the first active immune barrier in the
central nervous system. They fulfill multiple functions across development and adulthood …

The final stage of brain development is associated with the generation and maturation of
neuronal synapses. However, the same period is also associated with a peak in synapse …

Background Interactions between neurons, astrocytes, and microglia critically influence
neuroinflammatory responses to insult in the central nervous system. In vitro astrocyte and …

The past decade has witnessed a revolution in our understanding of microglia. These
immune cells were shown to actively remodel neuronal circuits, leading to propose new …

Microglia originate from erythromyeloid progenitors (EMPs) in the yolk sac and develop in
the forming CNS. Microglia are fundamental for the development and function of a healthy …

Microglial cells are the resident macrophages of the central nervous system (CNS) and are
mainly known for their roles in neuropathologies. However, major recent developments have …

Environmental challenges to the maternal immune system during pregnancy have been
associated with an increase in the frequency of neurodevelopmental disorders such as …

Many diverse factors, ranging from stress to infections, can perturb brain homeostasis and
alter the physiological activity of microglia, the immune cells of the central nervous system …

Microglial cells are the resident immune cells of the central nervous system. They are
essential for normal functioning, maintenance of tissue integrity, clearance of dying neurons …