Animal models are crucial for improving our understanding of human pathogenesis,
enabling researchers to identify therapeutic targets and test novel drugs. In the current …

The liver is the most essential organ of the body performing vital functions. Hepatic disorders
affect the physiological and biochemical functions of the body. These disorders include …

The liver, a component of the gastrointestinal tract, is one of the most important organs in the
human body. The liver performs over 500 functions to promote physiological homeostasis. In …

Alcoholic liver disease (ALD) is the most common chronic liver disease in the Western world,
and it persists at a high prevalence. Understanding the pathophysiology and successful …

Most research involving alcohol and cancer concerns the relationship between alcohol
consumption and cancer risk and the mechanisms of carcinogenesis. This review relates the …

Alcoholic liver disease (ALD) remains to be a worldwide health problem. It is generally
accepted that oxidative stress plays critical roles in the pathogenesis of ALD, and antioxidant …

Abstract Binge drinking (BD), ie, consuming a large amount of alcohol in a short period of
time, is an increasing public health issue. Though no clear definition has been adopted …

Chronic ethanol consumption disrupts several metabolic pathways including β-oxidation
and lipid biosynthesis, facilitating the development of alcoholic fatty liver disease. Many of …

Heavy alcohol consumption is the dominant risk factor for chronic pancreatitis (CP);
however, treatment and prevention strategies for alcoholic chronic pancreatitis (ACP) …

Alcoholic liver disease (ALD) is still a global health concern. Long-term alcohol intake alters
the gut microbiota diversity and metabolic activity, and causes intestinal barrier dysfunction …