Plasmodium vivax is the most widespread human malaria, putting 2.5 billion people at risk of
infection. Its unique biological and epidemiological characteristics pose challenges to …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

The ancient biological'arms race'between microbial pathogens and humans has shaped
genetic variation in modern populations, and this has important implications for the growing …

Background Current understanding of the spatial epidemiology and geographical
distribution of Plasmodium vivax is far less developed than that for P. falciparum …

Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …

Plasmodium vivax shows a strict host tropism for reticulocytes. We identified transferrin
receptor 1 (TfR1) as the receptor for P. vivax reticulocyte-binding protein 2b (PvRBP2b). We …

Blood group variants are characteristic of population groups, and can show conspicuous
geographic patterns. Interest in the global prevalence of the Duffy blood group variants is …

Background A research priority for Plasmodium vivax malaria is to improve our
understanding of the spatial distribution of risk and its relationship with the burden of P. vivax …

More than a century after the discovery of Plasmodium spp. parasites, the pathogenesis of
severe malaria is still not well understood. The majority of malaria cases are caused by …

Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …