Organ transplantation has developed over the past 50 years to reach the sophisticated and
integrated clinical service of today through several advances in science. One of the most …

This article provides a comprehensive, up-to-date review of methods to prevent early and
late renal-allograft loss and to improve long-term outcomes in patients. The authors focus …

Background More than 80% of donor lungs are potentially injured and therefore not
considered suitable for transplantation. With the use of normothermic ex vivo lung perfusion …

Background Severe primary graft dysfunction (PGD) of grade 3 (PGD3) is a common serious
complication following lung transplantation. We aimed to assess physiological donor lung …

BACKGROUND: The inhibition of cellular metabolism induced by hypothermia obviates the
possibility of substantial reparative processes occurring during organ preservation. The aim …

During heart transplantation, storage in cold preservation solution is thought to protect the
organ by slowing metabolism, providing osmotic support and minimizing ischaemia …

The activation of host's innate and adaptive immune systems can lead to acute and chronic
graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to …

OBJECTIVE: Normothermic ex vivo lung perfusion is a novel method to evaluate and
improve the function of injured donor lungs. We reviewed our experience with 50 …

Organ transplantation is the most effective therapy for patients with end-stage disease.
Preservation solutions and techniques are crucial for donor organ quality, which is directly …

In the pursuit of dendrimer alternatives, hyperbranched polymers have found increasing
interest from academia and industry in a broad range of fields due to their topological and …