Progesterone and progesterone receptors (PRs) are essential for the development and
cyclical regulation of hormone-responsive tissues including the breast and reproductive …

Ulcerative colitis and Crohn's disease are the 2 major phenotypes of inflammatory bowel
disease (IBD), which are influenced by a complex interplay of immunological and genetic …

Pediatric-onset colitis and inflammatory bowel disease (IBD) have significant effects on the
growth of infants and children, but the etiopathogenesis underlying disease subtypes …

It remains a great challenge to achieve sufficient cancer classification accuracy with the
entire set of genes, due to the high dimensions, small sample size, and big noise of gene …

Functional gastrointestinal disorders (FGIDs) and IBDs are two of the most prevalent
disorders of the GI tract and consume a significant proportion of healthcare resources …

Activating mutations in receptor guanylyl cyclase C (GC-C), the target of gastrointestinal
peptide hormones guanylin and uroguanylin, and bacterial heat-stable enterotoxins cause …

Animal models are widely used for biomedical studies and drug evaluation. The small
intestine plays key roles in nutrient absorption, hormone secretion, microbiota defense and …

Receptor Guanylyl Cyclase C (GC-C) was initially characterized as an important regulator of
intestinal fluid and ion homeostasis. Recent findings demonstrate that GC-C is also causally …

Abstract Background and Aims The aim of this study was to investigate the genome-wide
DNA methylation status in treatment-naïve ulcerative colitis [UC], and to explore the …

Background Several serious attempts to treat colorectal cancer have been made in recent
decades. However, no effective treatment has yet been discovered due to the complexities …