Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate
various biological effects including membrane excitability, synaptic transmission and …

Several neurochemical systems converge in the prefrontal cortex (PFC) to regulate cognitive
and motivated behaviors. A rich network of endogenous opioid peptides and receptors …

In some models, animals approach aversive stimuli more than those housed in an enriched
environment. Here, we found that male mice in an impoverished and unstimulating (ie …

Mu-opioid receptor (μ-OR) signaling in forebrain sites including nucleus accumbens (Acb)
and ventromedial prefrontal cortex (vmPFC) modulates reward-driven feeding and may play …

This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Subregions within insular cortex and medial prefrontal cortex (mPFC) have been implicated
in eating disorders; however, the way these brain regions interact to produce dysfunctional …

The brain is a remarkably complex organ responsible for a wide range of functions,
including the modulation of emotional states and movement. Neuronal circuits are believed …

Background A better understanding of the neural mechanisms regulating impaired satiety to
palatable foods is essential to treat hyperphagia linked with obesity. The satiation hormone …

The medial frontal cortex (MFC) in rodents emits rhythmic activity that is entrained to the
animal's licking cycle during consumption and encodes the value of consumed fluids. These …

Pharmacological, optogenetic, and chemogenetic mapping studies of neurobehavioral
causation are revealing an often-remarkable degree of cortical localization for appetitive …