Neurodegenerative disorders (ie, Alzheimer's disease, Parkinson's disease, amyotrophic
lateral sclerosis, and spinal cord injury) represent a great problem worldwide and are …

The delivery of therapeutic molecules to the brain remains an unsolved problem to the
researchers due to the existence of the blood–brain barrier (BBB), which halts the entry of …

Intranasal administration has gained an increasing interest for brain drug delivery since it
allows direct transport through neuronal pathways, which can be quite advantageous for …

Neurodegenerative disorders (NDs) are highly prevalent among the aging population. It
affects primarily the central nervous system (CNS) but the effects are also observed in the …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, for which
no effective treatment is yet available to either slow or terminate it. Recent advances in gene …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, with a median
survival of only 2 to 4 years. Riluzole, a drug commonly used in the management of ALS …

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a
progressive neurodegenerative disease that affects both upper and lower motor neurons …

In the present study, SEL was loaded in a lipid nanocarrier (LNC) formulation with a P-gp
pump inhibitor ie, Quercetin (QUR) for improving the bioavailability of the SEL in the brain …

Recently, several nutraceutical products are being explored to validate their neuroprotective
claims as well as clinical prospects in terms of balancing neurosignaling mechanisms …

The present work-study the decreasing fluoride ions toxicity on the rat heart via loading them
on the chitosan nanoparticles (Cs NPs) surface to form the biologically compatible …