Synthesis and anticancer mechanisms of zinc (II)-8-hydroxyquinoline complexes with 1, 10-phenanthroline ancillary ligands

LQ Du, TY Zhang, XM Huang, Y Xu, MX Tan… - Dalton …, 2023 - pubs.rsc.org
Twenty new zinc (II) complexes with 8-hydroxyquinoline (H-Q1–H-Q6) in the presence of 1,
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …

Antitumor studies evaluation of triphenylphosphine ruthenium complexes with 5, 7-dihalo-substituted-8-quinolinoline targeting mitophagy pathways

ZF Wang, XQ Huang, RC Wu, Y Xiao… - Journal of Inorganic …, 2023 - Elsevier
Both ruthenium-containing complexes and 8-quinolinoline compounds have emerged as a
potential novel agent for malignant tumor therapy. Here, three triphenylphosphine ruthenium …

Novel zinc (II)− curcumin molecular probes bearing berberine and jatrorrhizine derivatives as potential mitochondria-targeting anti-neoplastic drugs

SH Zhang, ZF Wang, H Tan - European Journal of Medicinal Chemistry, 2022 - Elsevier
Berberine and jatrorrhizine are major bioactive components that are emerging as potential
anti-cancer drugs. However, no zinc (II)–berberine/jatrorrhizine–curcumin compounds have …

[HTML][HTML] Drug repositioning of disulfiram induces endometrioid epithelial ovarian cancer cell death via the both apoptosis and cuproptosis pathways

Y Gan, T Liu, W Feng, L Wang, LI Li, Y Ning - Oncology Research, 2023 - ncbi.nlm.nih.gov
Various therapeutic strategies have been developed to overcome ovarian cancer. However,
the prognoses resulting from these strategies are still unclear. In the present work, we …

Density Functional Theory-Guided Photo-Triggered Anticancer Activity of Curcumin-Based Zinc (II) Complexes

R Kushwaha, V Singh, S Peters, AK Yadav… - The Journal of …, 2023 - ACS Publications
Photodynamic therapy (PDT) has evolved as a new therapeutic modality for cancer
treatment with fewer side effects and drug resistance. Curcumin exhibits PDT activity, but its …

Platinum (II) 5-substituted-8-hydroxyquinoline coordination compounds induces mitophagy-mediated apoptosis in A549/DDP cancer cells

Y Yang, LQ Du, Y Huang, CJ Liang, QP Qin… - Journal of Inorganic …, 2023 - Elsevier
For the first time, two new mononuclear platinum (II) coordination compounds,[Pt
(L1)(DMSO) Cl](PtL1) and [Pt (L2)(DMSO) Cl](PtL2) with the 5-(ethoxymethyl)-8 …

A new class of nickel (ii) oxyquinoline–bipyridine complexes as potent anticancer agents induces apoptosis and autophagy in A549/DDP tumor cells through …

ZF Wang, QC Wei, JX Li, Z Zhou, SH Zhang - Dalton Transactions, 2022 - pubs.rsc.org
A new class of nickel (II) oxyquinoline–bipyridine complexes, namely,[Ni (La1) 2
(Lb6)](Ni1),[Ni (La1) 2 (Lb2)]· CH3OH (Ni2),[Ni (La7) 2 (Lb11)]· 2H2O (Ni3),[Ni (La1) 2 …

Novel glycosylation zinc (II)–cryptolepine complexes perturb mitophagy pathways and trigger cancer cell apoptosis and autophagy in SK-OV-3/DDP cells

Z Zhou, LQ Du, XM Huang, LG Zhu, QC Wei… - European Journal of …, 2022 - Elsevier
With the aim of shedding some light on the mechanism of action of zinc (II) complexes in
antiproliferative processes and molecular signaling pathways, three novel glycosylated zinc …

Highly efficient and facile removal of As (V) from water by using Pb‐MOF with higher stable and fluorescence

C Zhang, Y Qin, Z Ke, L Yin, Y Xiao… - Applied Organometallic …, 2023 - Wiley Online Library
Metal–organic framework (MOF) materials are promising adsorbents for removing As (V)
from sodium arsenate aqueous solutions, because of their high porosity and functional …

Cell nucleus localization and high anticancer activity of quinoline–benzopyran rhodium (III) metal complexes as therapeutic and fluorescence imaging agents

ZF Wang, XL Nai, Y Xu, FH Pan, FS Tang, QP Qin… - Dalton …, 2022 - pubs.rsc.org
Four novel rhodium (III) complexes,[RhIII (QB1) Cl3 (DMSO)](RhN1),[RhIII (QB2) Cl3
(CH3OH)]· CH3OH (RhN2),[RhIII (QB3) Cl3 (CH3OH)]· CH3OH (RhS), and [RhIII (QB4) Cl3 …