Background: Mild cognitive impairment (MCI) is an important stage between the normal
cognitive decline of aging and dementia. The aim of this study was to compare and …

Coordinated interactions between the central and autonomic nervous systems are crucial for
survival due to the inherent propensity for human behavior to make errors. In our ever …

The heart and brain have bi-directional influences on each other, including autonomic
regulation and hemodynamic connections. Heart rate variability (HRV) measures variation in …

Neurodegenerative diseases, which frequently present with neuropsychiatric symptoms
related to prefrontal cortical dysfunction, can alter the integrity of the neural networks …

Background Continuous assessment and remote monitoring of cognitive function in
individuals with mild cognitive impairment (MCI) enables tracking therapeutic effects and …

Occurrence of amyloid-β (Aβ) aggregation in brain begins before the clinical onset of
Alzheimer's disease (AD), as preclinical AD. Studies have reported that sleep problems and …

While mild cognitive impairment (MCI) has been classified into amnestic MCI (aMCI) and
nonamnestic MCI (naMCI), the neuropathological bases of these two subtypes remain …

Background Despite the emerging clinical relevance of heart rate variability (HRV) as a
potential biomarker of cognitive decline and as a candidate target for intervention, there is a …

Coronavirus Disease 2019 (COVID-19) pandemic-triggered mortality is significantly higher
in older than in younger populations worldwide. Alzheimer's disease (AD) is related to aging …

Background Social support is important to psychological well‐being in late life. However,
findings in the literature regarding its effects are mixed, less information is available for …