A bio-social model during the first 1000 days optimizes healthcare for children with developmental disabilities

MS Scher - Biomedicines, 2022 - mdpi.com
Most children with developmental disabilities (DD) live in resource-limited countries (LMIC)
or high-income country medical deserts (HICMD). A social contract between healthcare …

Impact of stress on brain morphology: insights into structural biomarkers of stress-related disorders

R Andero, M Cano, I Marin-Blasco… - Current …, 2024 - ingentaconnect.com
Exposure to acute and chronic stress has a broad range of structural effects on the brain.
The brain areas commonly targeted in the stress response models include the …

[HTML][HTML] Fetal brain tissue annotation and segmentation challenge results

K Payette, HB Li, P de Dumast, R Licandro, H Ji… - Medical Image …, 2023 - Elsevier
In-utero fetal MRI is emerging as an important tool in the diagnosis and analysis of the
developing human brain. Automatic segmentation of the developing fetal brain is a vital step …

[HTML][HTML] Role of gastrointestinal health in managing children with autism spectrum disorder

M Al-Beltagi, NK Saeed, AS Bediwy… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Children with autism spectrum disorders (ASD) or autism are more prone to gastrointestinal
(GI) disorders than the general population. These disorders can significantly affect their …

Applications of advanced diffusion MRI in early brain development: a comprehensive review

M DiPiero, PG Rodrigues, A Gromala… - Brain Structure and …, 2023 - Springer
Brain development follows a protracted developmental timeline with foundational processes
of neurodevelopment occurring from the third trimester of gestation into the first decade of …

Gene-environment interactions during the first thousand days influence childhood neurological diagnosis

MS Scher - Seminars in Pediatric Neurology, 2022 - Elsevier
Gene-environment (G x E) interactions significantly influence neurologic outcomes. The
maternal-placental-fetal (MPF) triad, neonate, or child less than 2 years may first exhibit …

Harnessing the power of advanced fetal neuroimaging to understand in utero footprints for later neuropsychiatric disorders

J De Asis-Cruz, C Limperopoulos - Biological Psychiatry, 2023 - Elsevier
Adverse intrauterine events may profoundly impact fetal risk for future adult diseases. The
mechanisms underlying this increased vulnerability are complex and remain poorly …

[HTML][HTML] Interdisciplinary fetal-neonatal neurology training applies neural exposome perspectives to neurology principles and practice

MS Scher - Frontiers in Neurology, 2024 - frontiersin.org
An interdisciplinary fetal-neonatal neurology (FNN) program over the first 1,000 days
teaches perspectives of the neural exposome that are applicable across the life span. This …

Asc: Appearance and structure consistency for unsupervised domain adaptation in fetal brain mri segmentation

Z Xu, H Gong, X Wan, H Li - … on Medical Image Computing and Computer …, 2023 - Springer
Automatic tissue segmentation of fetal brain images is essential for the quantitative analysis
of prenatal neurodevelopment. However, producing voxel-level annotations of fetal brain …

Toward a more informative representation of the fetal–neonatal brain connectome using variational autoencoder

JH Kim, J De Asis-Cruz, D Krishnamurthy… - Elife, 2023 - elifesciences.org
Recent advances in functional magnetic resonance imaging (fMRI) have helped elucidate
previously inaccessible trajectories of early-life prenatal and neonatal brain development …