Controlling the biodistribution and clearance of nanomedicines

H Cabral, J Li, K Miyata, K Kataoka - Nature Reviews Bioengineering, 2024 - nature.com
Nanomedicines improve drug bioavailability, the dose–response relationship, targeting
ability, efficacy and safety compared to conventional freely administered drugs …

[HTML][HTML] Cancer nanomedicine: emerging strategies and therapeutic potentials

M Xu, X Han, H Xiong, Y Gao, B Xu, G Zhu, J Li - Molecules, 2023 - mdpi.com
Cancer continues to pose a severe threat to global health, making pursuing effective
treatments more critical than ever. Traditional therapies, although pivotal in managing …

[HTML][HTML] Degradable polymeric bio (nano) materials and their biomedical applications: A comprehensive overview and recent updates

K Kuperkar, LI Atanase, A Bahadur, IC Crivei… - Polymers, 2024 - mdpi.com
Degradable polymers (both biomacromolecules and several synthetic polymers) for
biomedical applications have been promising very much in the recent past due to their low …

Dendritic Nanomedicine with Boronate Bonds for Augmented Chemo‐Immunotherapy via Synergistic Modulation of Tumor Immune Microenvironment

Y Li, Y Wu, Z Fang, Y Zhang, H Ding, L Ren… - Advanced …, 2024 - Wiley Online Library
Unsatisfied tumor accumulation of chemotherapeutic drugs and a complicated
immunosuppressive microenvironment diminish the immune response rate and the …

[HTML][HTML] Pluronic F-68 and F-127 based nanomedicines for advancing combination cancer therapy

NU Khaliq, J Lee, S Kim, D Sung, H Kim - Pharmaceutics, 2023 - mdpi.com
Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene
oxide)(PEO) chains linked via a central hydrophobic polypropylene oxide (PPO). Owing to …

[HTML][HTML] Exosome-sheathed ROS-responsive nanogel to improve targeted therapy in perimenopausal depression

Y Hu, M Zhao, H Wang, Y Guo, X Cheng… - Journal of …, 2023 - Springer
The development of natural membranes as coatings for nanoparticles to traverse the blood-
brain barrier (BBB) presents an effective approach for treating central nervous system (CNS) …

A mitochondrial nanoguard modulates redox homeostasis and bioenergy metabolism in diabetic peripheral neuropathy

Y Yao, X Lei, Y Wang, G Zhang, H Huang, Y Zhao… - ACS …, 2023 - ACS Publications
As a major late complication of diabetes, diabetic peripheral neuropathy (DPN) is the
primary reason for amputation. Nevertheless, there are no wonder drugs available …

[HTML][HTML] Application of nanoparticles in cancer treatment: a concise review

M Sell, AR Lopes, M Escudeiro, B Esteves… - Nanomaterials, 2023 - mdpi.com
Timely diagnosis and appropriate antitumoral treatments remain of utmost importance, since
cancer remains a leading cause of death worldwide. Within this context, nanotechnology …

[HTML][HTML] Biodegradable polyester-based nano drug delivery system in cancer chemotherapy: a review of recent progress (2021–2023)

Z Wang, M Xiao, F Guo, Y Yan, H Tian… - … in Bioengineering and …, 2023 - frontiersin.org
Cancer presents a formidable threat to human health, with the majority of cases currently
lacking a complete cure. Frequently, chemotherapy drugs are required to impede its …

[HTML][HTML] Recent advances in cell membrane coated-nanoparticles as drug delivery systems for tackling urological diseases

C Yao, D Zhang, H Wang, P Zhang - Pharmaceutics, 2023 - mdpi.com
Recent studies have revealed the functional roles of cell membrane coated-nanoparticles
(CMNPs) in tackling urological diseases, including cancers, inflammation, and acute kidney …