Antimicrobial peptides secreted by equine mesenchymal stromal cells inhibit the growth of bacteria commonly found in skin wounds

RM Harman, S Yang, MK He… - Stem cell research & …, 2017 - Springer
Background The prevalence of chronic skin wounds in humans is high, and treatment is
often complicated by the presence of pathogenic bacteria. Therefore, safe and innovative …

Emerging pharmacological therapies for ARDS: COVID-19 and beyond

S Horie, B McNicholas, E Rezoagli, T Pham… - Intensive care …, 2020 - Springer
ARDS, first described in 1967, is the commonest form of acute severe hypoxemic respiratory
failure. Despite considerable advances in our knowledge regarding the pathophysiology of …

Mesenchymal stem cells in homeostasis and systemic diseases: hypothesis, evidences, and therapeutic opportunities

FJ Vizoso, N Eiro, L Costa, P Esparza… - International journal of …, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are present in all organs and tissues, playing a well-known
function in tissue regeneration. However, there is also evidence indicating a broader role of …

Mesenchymal stem cell-based therapy as a new therapeutic approach for acute inflammation

K Abdolmohammadi, T Mahmoudi, M Alimohammadi… - Life Sciences, 2023 - Elsevier
Acute inflammatory diseases such as acute colitis, kidney injury, liver failure, lung injury,
myocardial infarction, pancreatitis, septic shock, and spinal cord injury are significant causes …

Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential

E Gorman, J Millar, D McAuley… - Expert review of …, 2021 - Taylor & Francis
Introduction: Mesenchymal stromal (stem) cell (MSC) therapies are emerging as a promising
therapeutic intervention in patients with Acute Respiratory Distress Syndrome (ARDS) and …

Mesenchymal stem cells-derived extracellular vesicles in acute respiratory distress syndrome: a review of current literature and potential future treatment options

TG Shah, D Predescu, S Predescu - Clinical and Translational Medicine, 2019 - Springer
Acute respiratory distress syndrome (ARDS) is a life-threatening inflammatory lung condition
associated with significant morbidity and mortality. Unfortunately, the current treatment for …

Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome

M Lopes-Pacheco, C Robba, PRM Rocco… - Cell biology and …, 2020 - Springer
The acute respiratory distress syndrome (ARDS) is a multifaceted lung disorder in which no
specific therapeutic intervention is able to effectively improve clinical outcomes. Despite an …

Extracellular Vesicles from Interferon-γ–primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli–induced Acute Lung Injury in Rats

AK Varkouhi, M Jerkic, L Ormesher, S Gagnon… - …, 2019 - pubs.asahq.org
Abstract Editor's Perspective What We Already Know about This Topic Mesenchymal stromal
cells are multipotent adult stem cells with the capacity to differentiate into multiple cell types …

Intravenous infusion of human adipose mesenchymal stem cells modifies the host response to lipopolysaccharide in humans: a randomized, single-blind, parallel …

D Perlee, LA van Vught, BP Scicluna, A Maag… - Stem Cells, 2018 - academic.oup.com
In experimental models, mesenchymal stem cells (MSCs) can modulate various immune
responses implicated in the pathogenesis of sepsis. Intravenous injection of …

Insights into the use of mesenchymal stem cells in COVID-19 mediated acute respiratory failure

N Durand, J Mallea, AC Zubair - NPJ Regenerative medicine, 2020 - nature.com
The emergence of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) at the
end of 2019 in Hubei province China, is now the cause of a global pandemic present in over …