D-dimer: old dogmas, new (COVID-19) tricks

G Lippi, F Mullier, EJ Favaloro - Clinical Chemistry and Laboratory …, 2023 - degruyter.com
D-dimer is a fibrin degradation product encompassing multiple cross-linked D domains
and/or E domains present in the original fibrinogen molecule, whose generation is only …

[HTML][HTML] The intersection of obesity and (long) COVID-19: Hypoxia, thrombotic inflammation, and vascular endothelial injury

M Xiang, X Wu, H Jing, VA Novakovic… - Frontiers in …, 2023 - frontiersin.org
The role of hypoxia, vascular endothelial injury, and thrombotic inflammation in worsening
COVID-19 symptoms has been generally recognized. Damaged vascular endothelium plays …

Effect of thromboprophylaxis on clinical outcomes after COVID-19 hospitalization

TY Wang, AS Wahed, A Morris… - Annals of internal …, 2023 - acpjournals.org
Background: Patients hospitalized with COVID-19 have an increased incidence of
thromboembolism. The role of extended thromboprophylaxis after hospital discharge is …

Thrombotic Complications in Children with COVID-19 and MIS-C

R Kumar, MJ Rivkin, L Raffini - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) associated coagulopathy is multifactorial
and involves inflammation driven hypercoagulability, endothelial dysfunction, platelet …

It's in the blood: a review of the hematological system in SARS-CoV-2-associated COVID-19

JV Harte, C Coleman-Vaughan… - Critical Reviews in …, 2023 - Taylor & Francis
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to an unprecedented global healthcare crisis. While SARS-CoV-2-associated COVID-19 …

[HTML][HTML] Need for a standardized translational drug development platform: Lessons learned from the repurposing of drugs for COVID-19

F Assmus, JS Driouich, R Abdelnabi, L Vangeel… - Microorganisms, 2022 - mdpi.com
In the absence of drugs to treat or prevent COVID-19, drug repurposing can be a valuable
strategy. Despite a substantial number of clinical trials, drug repurposing did not deliver on …

COVID-19: hypercoagulability

A Cuker, F Peyvandi - uptodate [Internet]. Available from: https://www …, 2021 - uptodate.com
COVID-19: Hypercoagulability - UpToDate wolters kluwer English Why UpToDate? Product
Editorial Subscription Options Subscribe Sign in Learn how UpToDate can help you. Select the …

Role of Therapeutic Anticoagulation in COVID-19: The Current Situation

MS Rahi, J Parekh, P Pednekar, M Mudgal, V Jindal… - Hematology …, 2023 - mdpi.com
Thrombotic complications from COVID-19 are now well known and contribute to significant
morbidity and mortality. Different variants confer varying risks of thrombotic complications …

Effectiveness of Drug Repurposing and Natural Products Against SARS-CoV-2: A Comprehensive Review

PA Velásquez, JC Hernandez, E Galeano… - Clinical …, 2024 - Taylor & Francis
Abstract The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a
betacoronavirus responsible for the COVID-19 pandemic, causing respiratory disorders, and …

To prophylax or not, and how much and how long? Controversies in VTE prevention for medical inpatients, including COVID-19 inpatients

AC Spyropoulos - Hematology, 2022 - ashpublications.org
The field of thromboprophylaxis for acutely ill medical patients, including those hospitalized
for COVID-19, is rapidly evolving both in the inpatient setting and the immediate post …