Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Fixed-intensity exercise tests to measure exertional dyspnoea in chronic heart and lung populations: a systematic review

T Palmer, SJ Obst, CR Aitken, J Walsh… - European …, 2023 - Eur Respiratory Soc
Introduction Exertional dyspnoea is the primary diagnostic symptom for chronic
cardiopulmonary disease populations. Whilst a number of exercise tests are used, there …

[HTML][HTML] LABA/LAMA as first-line therapy for COPD: a summary of the evidence and guideline recommendations

M Miravitlles, T Kawayama, M Dreher - Journal of Clinical Medicine, 2022 - mdpi.com
Inhaled bronchodilators (alone or in combination) are the cornerstone of treatment for
symptomatic patients with COPD, either as initial/first-line treatment or for second …

[HTML][HTML] Tiotropium/olodaterol: a review in COPD

HA Blair - Drugs, 2019 - Springer
Abstract Tiotropium/olodaterol (Stiolto® Respimat®; Spiolto® Respimat®) is an inhaled fixed-
dose combination of the long-acting muscarinic antagonist tiotropium bromide (hereafter …

Current developments and future directions in COPD

AG Mathioudakis, LEGW Vanfleteren… - European …, 2020 - Eur Respiratory Soc
The European Respiratory Society journals publish respiratory research and policy
documents of the highest quality, offering a platform for the exchange and promotion of …

[HTML][HTML] Efficacy of tiotropium/olodaterol compared with tiotropium as a first-line maintenance treatment in patients with COPD who are naïve to LAMA, LABA and ICS …

R Buhl, A de la Hoz, W Xue, D Singh, GT Ferguson - Advances in Therapy, 2020 - Springer
Introduction The efficacy of tiotropium/olodaterol compared with tiotropium in patients with
chronic obstructive pulmonary disease (COPD) has been demonstrated in a large clinical …

Automated O2 titration alone or with high-flow nasal cannula during walking exercise in chronic lung diseases

FA Vézina, PA Bouchard, É Breton-Gagnon… - Respiratory …, 2024 - rc.rcjournal.com
BACKGROUND: Exercise-induced O2 desaturation contributes to dyspnea and exercise
intolerance in various respiratory diseases. This study assessed whether automated O2 …

Why treatment efficacy on breathlessness in laboratory but not daily life trials? The importance of standardized exertion

M Ekström - Current opinion in supportive and palliative care, 2019 - journals.lww.com
Why treatment efficacy on breathlessness in laboratory but n... : Current Opinion in
Supportive and Palliative Care Why treatment efficacy on breathlessness in laboratory but …

Future concepts in bronchodilation for COPD: dual-versus monotherapy

D Singh, JF Donohue, IH Boucot… - European …, 2021 - Eur Respiratory Soc
Most patients with COPD are recommended to initiate maintenance therapy with a single
long-acting bronchodilator, such as a long-acting muscarinic antagonist or long-acting β2 …

[HTML][HTML] Effects of tiotropium/olodaterol on activity-related breathlessness, exercise endurance and physical activity in patients with COPD: narrative review with meta …

F Maltais, A de la Hoz, R Casaburi, D O'Donnell - Advances in therapy, 2021 - Springer
One of the most debilitating symptoms of chronic obstructive pulmonary disease (COPD) is
breathlessness, which leads to avoidance of physical activities in daily living and hastens …