Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

[HTML][HTML] Application of magnetic nanoparticles in nucleic acid detection

C Tang, Z He, H Liu, Y Xu, H Huang, G Yang… - Journal of …, 2020 - Springer
Nucleic acid is the main material for storing, copying, and transmitting genetic information.
Gene sequencing is of great significance in DNA damage research, gene therapy, mutation …

LAMP diagnostics at the point-of-care: emerging trends and perspectives for the developer community

TJ Moehling, G Choi, LC Dugan, M Salit… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Over the past decade, loop-mediated isothermal amplification (LAMP)
technology has played an important role in molecular diagnostics. Amongst numerous …

[PDF][PDF] Molecular and immunological diagnostic tests of COVID-19: current status and challenges

T Kilic, R Weissleder, H Lee - IScience, 2020 - cell.com
Rapid spread of coronavirus disease 2019 (COVID-19) is ravaging the globe. Since its first
report in December 2019, COVID-19 cases have exploded to over 14 million as of July …

Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics

Z Li, X Xu, D Wang, X Jiang - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) has extensively promoted the
application of nucleic acid testing technology in the field of clinical testing. The most widely …

[PDF][PDF] Fighting COVID-19: integrated micro-and nanosystems for viral infection diagnostics

Z Qin, R Peng, IK Baravik, X Liu - Matter, 2020 - cell.com
The pandemic of coronavirus disease 2019 (COVID-19) highlights the importance of rapid
and sensitive diagnostics of viral infection that enables the efficient tracing of cases and the …

[HTML][HTML] Targets, pitfalls and reference materials for liquid biopsy tests in cancer diagnostics

E Geeurickx, A Hendrix - Molecular aspects of medicine, 2020 - Elsevier
Assessment of cell free DNA (cfDNA) and RNA (cfRNA), circulating tumor cells (CTC) and
extracellular vesicles (EV) in blood or other bodily fluids can enable early cancer detection …

CRISPR-based diagnostics: Challenges and potential solutions toward point-of-care applications

A Ghouneimy, A Mahas, T Marsic, R Aman… - ACS Synthetic …, 2022 - ACS Publications
The COVID-19 pandemic has challenged the conventional diagnostic field and revealed the
need for decentralized Point of Care (POC) solutions. Although nucleic acid testing is …

[HTML][HTML] Current concepts, advances, and challenges in deciphering the human microbiota with metatranscriptomics

T Ojala, AE Häkkinen, E Kankuri, M Kankainen - Trends in Genetics, 2023 - cell.com
Metatranscriptomics refers to the analysis of the collective microbial transcriptome of a
sample. Its increased utilization for the characterization of human-associated microbial …