Centrifugal microfluidic method for enrichment and enzymatic extraction of severe acute respiratory syndrome coronavirus 2 RNA

R Turiello, LM Dignan, B Thompson, M Poulter… - Analytical …, 2022 - ACS Publications
The diversification of analytical tools for diagnosis of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is imperative for effective virus surveillance and transmission …

Periodontal disease: From the lenses of light microscopy to the specs of proteomics and next-generation sequencing

N Bostanci, K Bao, D Greenwood, A Silbereisen… - Advances in Clinical …, 2019 - Elsevier
Periodontal disease entails the inflammatory destruction of the tooth supporting
(periodontal) tissues as a result of polymicrobial colonization of the tooth surface in the form …

Mini review: clinical routine microbiology in the era of automation and digital health

S Leo, A Cherkaoui, G Renzi… - Frontiers in Cellular and …, 2020 - frontiersin.org
Clinical microbiology laboratories are the first line to combat and handle infectious diseases
and antibiotic resistance, including newly emerging ones. Although most clinical …

Disposable, pressure-driven, and self-contained cartridge with pre-stored reagents for automated nucleic acid extraction

W Han, J Shin, JH Shin - Sensors and Actuators B: Chemical, 2023 - Elsevier
Nucleic acid extraction is vital in many applications such as molecular diagnostics, genetic
engineering, and deoxyribonucleic acid (DNA) sequencing. Although recent advances in …

Application of CRISPR/Cas12a in the rapid detection of pathogens

Y Wang, T Yang, G Liu, L Xie, J Guo, W Xiong - Clinica Chimica Acta, 2023 - Elsevier
The combination of clustered regularly interspaced short palindromic repeats (CRISPR) and
its associated Cas protein is an effective gene-editing instrument. Among them, the CRISPR …

Liquid biopsy: early and accurate diagnosis of brain tumor

Z Yi, C Qu, Y Zeng, Z Liu - Journal of Cancer Research and Clinical …, 2022 - Springer
Noninvasive examination is an emerging area in the field of neuro-oncology. Liquid biopsy
captures the landscape of genomic alterations of brain tumors and revolutionizes the …

Characterization of high-yield Bacillus subtilis cysteine protease for diverse industrial applications

UR Keshapaga, K Jathoth, SS Singh, R Gogada… - Brazilian Journal of …, 2023 - Springer
Bacterial proteases have extensive applications in various fields of industrial microbiology.
In this study, protease-producing organisms were screened on skimmed milk agar media …

One‐Step Nucleic Acid Purification and Noise‐Resistant Polymerase Chain Reaction by Electrokinetic Concentration for Ultralow‐Abundance Nucleic Acid Detection

W Ouyang, J Han - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Nucleic acid amplification tests (NAATs) integrated on a chip hold great promise for point‐of‐
care diagnostics. Currently, nucleic acid (NA) purification remains time‐consuming and …

A method for sampling the living wood microbiome

W Arnold, J Gewirtzman, PA Raymond… - Methods in Ecology …, 2024 - Wiley Online Library
Efforts to characterize microbial life across diverse environments have progressed
tremendously, yet the microbiome of Earth's largest biomass reservoir—the wood of living …

Emerging lab-on-a-chip approaches for liquid biopsy in lung cancer: Status in ctcs and ctdna research and clinical validation

 Carvalho, G Ferreira, D Seixas… - Cancers, 2021 - mdpi.com
Simple Summary Lung cancer (LCa) remains the leading cause of cancer-related mortality
worldwide, with late diagnosis and limited therapeutic approaches still constraining patient's …