Recently, CRISPR-Cas system-based assays for bacterial detection have been developed.
The aim of this scoping review is to map existing evidence on the utilization of CRISPR-Cas …

Background End-stage renal disease is an irreversible status of kidney dysfunction that
reduces both renal and non-renal drug clearance. Accumulation of uremic toxins seems to …

The extraction of high-quality ribonucleic acid (RNA) from tissues and cells is a key step in
many biological assays. Guanidinium thiocyanate-phenol-chloroform (AGPC) is a widely …

Rotationally-driven lab-on-a-disc (LoaD) microfluidic systems are among the most promising
methods for realizing complex nucleic acid (NA) testing at the point-of-need (PoN). However …

Nucleic acid extraction from complex environmental and ancient tissue material is prone to
co‐extract inhibitory substances that make further molecular analysis difficult or impossible …

Circulating microRNAs (or miRNAs) in bodily fluids, are increasingly being highlighted as
promising diagnostic and predictive biomarkers for a broad range of pathologies. Although …

In light of regulatory considerations, there are ongoing efforts to identify Triton X-100 (TX-
100) detergent alternatives for use in the biological manufacturing industry to mitigate …

Molecular‐based approaches for biological source identification are of great interest in the
forensic community because of a lack of sensitivity and specificity in current methods. Micro …

Molecular diagnostics is a powerful technique for detecting pathogens with high sensitivity,
but it has complicated sample preparation procedures that rely not only on a manual …

Conventional DNA sample preparation methods involve tedious sample handling steps that
require numerous inhibitors of the polymerase chain reaction (PCR) and instrumentation to …