[HTML][HTML] Increased dopamine type 2 gene expression in the dorsal striatum in individuals with autism spectrum disorder suggests alterations in indirect pathway …

C Brandenburg, JJ Soghomonian, K Zhang… - Frontiers in Cellular …, 2020 - frontiersin.org
Autism spectrum disorder (ASD) is behaviorally defined and diagnosed by delayed and/or
impeded language, stereotyped repetitive behaviors, and difficulties with social interactions …

Effects of ventral striatum lesions on stimulus-based versus action-based reinforcement learning

KM Rothenhoefer, VD Costa, R Bartolo… - Journal of …, 2017 - Soc Neuroscience
Learning the values of actions versus stimuli may depend on separable neural circuits. In
the current study, we evaluated the performance of rhesus macaques with ventral striatum …

Movement-related coupling of human subthalamic nucleus spikes to cortical gamma

P Fischer, WJ Lipski, WJ Neumann, RS Turner, P Fries… - Elife, 2020 - elifesciences.org
Cortico-basal ganglia interactions continuously shape the way we move. Ideas about how
this circuit works are based largely on models those consider only firing rate as the …

Dimensionality, information and learning in prefrontal cortex

R Bartolo, RC Saunders, AR Mitz… - PLoS computational …, 2020 - journals.plos.org
Learning leads to changes in population patterns of neural activity. In this study we wanted
to examine how these changes in patterns of activity affect the dimensionality of neural …

Transcriptome sequencing implicates dorsal striatum-specific gene network, immune response and energy metabolism pathways in bipolar disorder

R Pacifico, RL Davis - Molecular psychiatry, 2017 - nature.com
Bipolar disorder (BD) is a highly heritable and heterogeneous mental illness whose
manifestations often include impulsive and risk-taking behavior. This particular phenotype …

A quantitative analysis of context-dependent remapping of medial frontal cortex neurons and ensembles

L Ma, JM Hyman, D Durstewitz, AG Phillips… - Journal of …, 2016 - Soc Neuroscience
The frontal cortex has been implicated in a number of cognitive and motivational processes,
but understanding how individual neurons contribute to these processes is particularly …

Striatal action-value neurons reconsidered

L Elber-Dorozko, Y Loewenstein - ELife, 2018 - elifesciences.org
It is generally believed that during economic decisions, striatal neurons represent the values
associated with different actions. This hypothesis is based on studies, in which the activity of …

Contralateral disconnection of the rat prelimbic cortex and dorsomedial striatum impairs cue-guided behavioral switching

PM Baker, ME Ragozzino - Learning & Memory, 2014 - learnmem.cshlp.org
Switches in reward outcomes or reward-predictive cues are two fundamental ways in which
information is used to flexibly shift response patterns. The rat prelimbic cortex and …

How immune-inflammatory processes link CNS and psychiatric disorders: classification and treatment implications

G Anderson, M Maes - … (Formerly Current Drug Targets-CNS & …, 2017 - ingentaconnect.com
In this article the emerging biological overlaps of CNS disorders and psychiatric conditions
are reviewed. Recent work has highlighted how immune-inflammatory processes and their …

Deficient dynamics of prefrontal-striatal and striatal-default mode network (DMN) neural circuits in internet gaming disorder

L Wang, Z Zhang, S Wang, M Wang, H Dong… - Journal of Affective …, 2023 - Elsevier
Background Studies have proven that individuals with internet gaming disorder (IGD) show
impaired cognitive control over game craving; however, the neural mechanism underlying …