[HTML][HTML] Injection of a dopamine type 2 receptor antagonist into the dorsal striatum disrupts choices driven by previous outcomes, but not perceptual inference
E Lee, M Seo, O Dal Monte… - Journal of …, 2015 - Soc Neuroscience
Decisions are often driven by a combination of immediate perception and previous
experience. In this study, we investigated how these two sources of information are …
experience. In this study, we investigated how these two sources of information are …
Dead rats, dopamine, performance metrics, and peacock tails: proxy failure is an inherent risk in goal-oriented systems
When a measure becomes a target, it ceases to be a good measure. For example, when
standardized test scores in education become targets, teachers may start “teaching to the …
standardized test scores in education become targets, teachers may start “teaching to the …
[HTML][HTML] Action-value comparisons in the dorsolateral prefrontal cortex control choice between goal-directed actions
It is generally assumed that choice between different actions reflects the difference between
their action values yet little direct evidence confirming this assumption has been reported …
their action values yet little direct evidence confirming this assumption has been reported …
Prefrontal cortical inactivations decrease willingness to expend cognitive effort on a rodent cost/benefit decision-making task
Personal success often necessitates expending greater effort for greater reward but, equally
important, also requires judicious use of our limited cognitive resources (eg, attention) …
important, also requires judicious use of our limited cognitive resources (eg, attention) …
[HTML][HTML] Brain-inspired meta-reinforcement learning cognitive control in conflictual inhibition decision-making task for artificial agents
F Robertazzi, M Vissani, G Schillaci, E Falotico - Neural Networks, 2022 - Elsevier
Conflictual cues and unexpected changes in human real-case scenarios may be detrimental
to the execution of tasks by artificial agents, thus affecting their performance. Meta-learning …
to the execution of tasks by artificial agents, thus affecting their performance. Meta-learning …
[HTML][HTML] Prefrontal signals precede striatal signals for biased credit assignment in motivational learning biases
J Algermissen, JC Swart, R Scheeringa… - Nature …, 2024 - nature.com
Actions are biased by the outcomes they can produce: Humans are more likely to show
action under reward prospect, but hold back under punishment prospect. Such motivational …
action under reward prospect, but hold back under punishment prospect. Such motivational …
Caudate stimulation enhances learning
Neuromodulation is a promising treatment modality for disorders of learning and memory,
offering the possibility of precise alteration of disordered neural circuits. Studies to date have …
offering the possibility of precise alteration of disordered neural circuits. Studies to date have …
[HTML][HTML] Regulating Prefrontal Cortex Activation: An Emerging Role for the 5-HT2A Serotonin Receptor in the Modulation of Emotion-Based Actions?
The prefrontal cortex (PFC) is involved in mediating important higher-order cognitive
processes such as decision making, prompting thereby our actions. At the same time, PFC …
processes such as decision making, prompting thereby our actions. At the same time, PFC …
Thalamocortical contribution to flexible learning in neural systems
MB Wang, MM Halassa - Network neuroscience, 2022 - direct.mit.edu
Animal brains evolved to optimize behavior in dynamic environments, flexibly selecting
actions that maximize future rewards in different contexts. A large body of experimental work …
actions that maximize future rewards in different contexts. A large body of experimental work …
[HTML][HTML] Aberrant neural signatures of decision-making: Pathological gamblers display cortico-striatal hypersensitivity to extreme gambles
Pathological gambling is an addictive disorder characterized by an irresistible urge to
gamble despite severe consequences. One of the hallmarks of pathological gambling is …
gamble despite severe consequences. One of the hallmarks of pathological gambling is …