[HTML][HTML] Hypericin inhibit alpha-coronavirus replication by targeting 3CL protease

Y Zhang, H Chen, M Zou, R Oerlemans, C Shao, Y Ren… - Viruses, 2021 - mdpi.com
The porcine epidemic diarrhea virus (PEDV) is an Alphacoronavirus (α-CoV) that causes
high mortality in infected piglets, resulting in serious economic losses in the farming industry …

Current Knowledge of the Antidepressant Activity of Chemical Compounds from Crocus sativus L.

R Matraszek-Gawron, M Chwil, K Terlecki… - Pharmaceuticals, 2022 - mdpi.com
Psychotropic effect of Crocus sativus L.(family Iridaceae) biologically active chemical
compounds are quite well documented and they can therefore be used in addition to the …

Identification of Bioactive Compounds in Plant Extracts of Greek Flora and Their Antimicrobial and Antioxidant Activity

A Tsakni, A Chatzilazarou, E Tsakali, AG Tsantes… - Separations, 2023 - mdpi.com
This study examined five species of the Lamiaceae family, Origanum vulgare L., Origanum
dictamnus L., Origanum majorana L., Mentha spicata L. and Lavandula angustifolia L., and …

Hypericum spp.: An update on the biological activities and metabolic profiles

M Marrelli, G Statti, F Conforti - Mini reviews in medicinal …, 2020 - ingentaconnect.com
Plants from the genus Hypericum, one genus of the Hypericaceae family, have attracted a lot
of attention for their potential pharmaceutical applications. Most of the studies in the …

[HTML][HTML] Hydrogel wound dressings containing bioactive compounds originated from traditional Chinese herbs: A review

D Yang, H Chen, H Wei, A Liu, DX Wei… - Smart Materials in …, 2023 - Elsevier
Various factors can cause skin defects, resulting in the loss of physiological functions and
even death due to severe concurrent infection. Dressings are often clinically used to fully …

How should the worldwide knowledge of traditional cancer healing be integrated with herbs and mushrooms into modern molecular pharmacology?

Y Kirdeeva, O Fedorova, A Daks, N Barlev… - Pharmaceuticals, 2022 - mdpi.com
Traditional herbal medicine (THM) is a “core” from which modern medicine has evolved over
time. Besides this, one third of people worldwide have no access to modern medicine and …

Antidepressant-like activity of hyperforin and changes in BDNF and zinc levels in mice exposed to chronic unpredictable mild stress

B Szewczyk, B Pochwat, B Muszyńska, W Opoka… - Behavioural Brain …, 2019 - Elsevier
Chronic unpredictable mild stress (CUMS)-a rodent model of depression mimics a variety of
neurochemical and behavioral alterations similar to those seen in human depression. This …

The In Vitro Assessment of Antibacterial and Antioxidant Efficacy in Rosa damascena and Hypericum perforatum Extracts against Pathogenic Strains in the Interplay …

M Antoniadou, G Rozos, N Vaiou, K Zaralis, C Ersanli… - Microorganisms, 2023 - mdpi.com
The rising demand for novel antibiotic agents prompts an investigation into natural
resources, notably plant-derived compounds. In this study, various extracts (aqueous …

Low‐glucose‐sensitive TRPC6 dysfunction drives hypoglycemia‐induced cognitive impairment in diabetes

C He, P Gao, Y Cui, Q Li, Y Li, Z Lu… - Clinical and …, 2020 - Wiley Online Library
Background Recurrent moderate hypoglycemia (RH), a major adverse effect of
hypoglycemic therapy in diabetic patients, is one of the main risk factors for cognitive …

Hypericum perforatum L. Nanoemulsion Mitigates Cisplatin-Induced Chemobrain via Reducing Neurobehavioral Alterations, Oxidative Stress, Neuroinflammation …

HMA Khalil, HMA El Henafy, IA Khalil, AF Bakr… - Toxics, 2023 - mdpi.com
Cisplatin (Cis) is a potent chemotherapeutic agent; however, it is linked with oxidative stress,
inflammation, and apoptosis, which may harmfully affect the brain. Hypericum perforatum …