The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

P Menu, JE Vince - Clinical & Experimental Immunology, 2011 - academic.oup.com
Summary While interleukin (IL)-1β plays an important role in combating the invading
pathogen as part of the innate immune response, its dysregulation is responsible for a …

[HTML][HTML] Host pathogen interactions in Helicobacter pylori related gastric cancer

M Chmiela, Z Karwowska, W Gonciarz… - World journal of …, 2017 - ncbi.nlm.nih.gov
Abstract Helicobacter pylori (H. pylori), discovered in 1982, is a microaerophilic, spiral-
shaped gram-negative bacterium that is able to colonize the human stomach. Nearly half of …

Helicobacter pylori–activated fibroblasts as a silent partner in gastric cancer development

G Krzysiek-Maczka, T Brzozowski… - Cancer and Metastasis …, 2023 - Springer
The discovery of Helicobacter pylori (Hp) infection of gastric mucosa leading to active
chronic gastritis, gastroduodenal ulcers, and MALT lymphoma laid the groundwork for …

IL-1RN VNTR polymorphism and genetic susceptibility to cervical cancer in Portugal

H Sousa, AM Santos, R Catarino, D Pinto… - Molecular biology …, 2012 - Springer
Human Papillomavirus infection is considered as the main etiological factor of cervical
cancer (ICC), although, the role of host genetic factors in ICC susceptibility has been …

The endocannabinoid, anandamide, acts as a novel inhibitor of LPS‐induced inflammasome activation in human gastric cancer AGS cell line: Involvement of CB1 and …

SS Sedeighzadeh, H Galehdari… - Mediators of …, 2021 - Wiley Online Library
Inflammasome activation is a pivotal step for the maturation of IL‐1β, which is involved in the
development and progression of gastric cancer (GC). Endocannabinoids, such as …

Impact of fumonisin B1 on the production of inflammatory cytokines by gastric and colon cell lines

M Mahmoodi, AM Alizadeh, H Sohanaki… - Iranian Journal of …, 2012 - ijaai.tums.ac.ir
Impact of Fumonisin B1 on the Production of Inflammatory Cytokines by Gastric and Colon Cell
Lines Page 1 Copyright© 2012, IRANIAN JOURNAL OF ALLERGY, ASTHMA AND …

Relationship of interleukin-1B gene promoter region polymorphism with Helicobacter pylori infection and gastritis

IB Ramis, JS Vianna, PCB Halicki, C Lara… - The Journal of Infection …, 2015 - jidc.org
Introduction: Helicobacter pylori infection is associated with gastritis, peptic ulcer disease
and gastric carcinoma. The severity of damage is determined by the interplay between …

Gastric cancer as a multifactorial disease

S Iravani - Annals of military and health sciences research, 2013 - brieflands.com
: Background: Gastric cancer is the fourth most common cancer and it is known as the
second leading cause of cancer deaths. Carcinogenesis ius a multifactorial process that is …

IL-1RN VNTR polymorphism as a susceptibility marker for nasopharyngeal carcinoma in Portugal

H Sousa, E Breda, AM Santos, R Catarino, D Pinto… - Archives of oral …, 2013 - Elsevier
BACKGROUND: Nasopharyngeal carcinoma (NPC) is a rare malignancy in Western
countries that is widely associated with the infection by Epstein–Barr virus (EBV). Several …

A possible role of IL-1RN gene polymorphism in the outcome of gastrointestinal diseases associated with H. pylori infection

R Mattar, SB Marques, AF Dos Santos… - Clinical and …, 2013 - Taylor & Francis
Objective To verify whether the variable number of tandem repeat (VNTR) polymorphism in
the IL-1RN gene that encodes the interleukin (IL)-1 receptor antagonist (IL-1Ra) plays a role …