The Ubiquitin–Proteasome System in Tumor Metabolism

J Wang, Y Xiang, M Fan, S Fang, Q Hua - Cancers, 2023 - mdpi.com
Simple Summary The reprogramming of tumor cell metabolism is an important char acteristic
of cancer, which provides the energy and biomacromolecules in tumor development …

Polyphenols alleviate metabolic disorders: the role of ubiquitin-proteasome system

W Gu, G Wu, G Chen, X Meng, Z Xie, S Cai - Frontiers in Nutrition, 2024 - frontiersin.org
Metabolic disorders include obesity, nonalcoholic fatty liver disease, insulin resistance and
type 2 diabetes. It has become a major health issue around the world. Ubiquitin-proteasome …

New insights for polyphenolic compounds as naturally inspired proteasome inhibitors

E Marchese, ME Gallo Cantafio, FA Ambrosio… - Pharmaceuticals, 2023 - mdpi.com
Polyphenols, an important class of natural products, are widely distributed in plant-based
foods. These compounds are endowed with several biological activities and exert protective …

Targeting of mitochondrial fission through natural flavanones elicits anti-myeloma activity

R Torcasio, ME Gallo Cantafio, C Veneziano… - Journal of Translational …, 2024 - Springer
Background Mitochondrial alterations, often dependent on unbalanced mitochondrial
dynamics, feature in the pathobiology of human cancers, including multiple myeloma (MM) …

GPER1 Activation Exerts Anti-Tumor Activity in Multiple Myeloma

ME Gallo Cantafio, R Torcasio, F Scionti, M Mesuraca… - Cells, 2023 - mdpi.com
G protein-coupled estrogen receptor 1 (GPER1) activation is emerging as a promising
therapeutic strategy against several cancer types. While GPER targeting has been widely …

Semisynthetic phytochemicals in cancer treatment: a medicinal chemistry perspective

M Arora, AK Singh, A Kumar, H Singh… - RSC Medicinal …, 2024 - pubs.rsc.org
Cancer is the uncontrolled proliferation of abnormal cells that invade other areas, spread to
other organs, and cause metastases, which is the most common cause of death. A review of …

Involvement of the ubiquitin-proteasome system in the regulation of the tumor microenvironment and progression

Y Huang, Y Gao, Z Lin, H Miao - Genes & Diseases, 2024 - Elsevier
The tumor microenvironment is a complex environment comprising tumor cells, non-tumor
cells, and other critical non-cellular components. Some studies about tumor …

Determination of bone marrow cell morphology in rat

JL Shan, GY Zhu, LH Su, XS Liang, J Fu… - Cellular and Molecular …, 2023 - cellmolbiol.org
The skeletal system of the body is responsible for important functions in the human body. In
addition to causing movement, this system also plays a role in the production of blood cells …