The blood-brain barrier (BBB) is vital for maintaining brain homeostasis by enabling an
exquisite control of exchange of compounds between the blood and the brain parenchyma …

Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead
to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed …

Astaxanthin (3, 3-dihydroxy-β, β-carotene-4, 4-dione) is a ketocarotenoid synthesized by
Haematococcus pluvialis/lacustris, Chromochloris zofingiensis, Chlorococcum …

Blood-brain barrier disruption occurs in the early stages of Alzheimer's disease. Recent
studies indicate a link between blood-brain barrier dysfunction and cognitive decline and …

Overproduced reactive oxygen and reactive nitrogen species (RONS) in the brain are
involved in the pathogenesis of several neurological diseases, such as Alzheimer's disease …

There is a lot of evidence showing that lipid peroxidation plays very important role in
development of various diseases, including neurodegenerative diseases and brain tumors …

Cerebral ischemic stroke is one of the leading causes of adult disability worldwide.
Reperfusion is the only therapeutic option with a lot of side effects. In the current study, we …