Metals play vital roles in nutrients and medicines and provide chemical functionalities that
are not accessible to purely organic compounds. At least 10 metals are essential for human …

NAMI-A ((ImH)[trans-RuCl4 (dmso-S)(Im)], Im= imidazole) and KP1019/1339
(KP1019=(IndH)[trans-RuCl4 (Ind) 2], Ind= indazole; KP1339= Na [trans-RuCl4 (Ind) 2]) are …

Excessive cellular oxidative stress is widely perceived as a key factor in pathophysiological
conditions and cancer development. Healthy cells use several mechanisms to maintain …

The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …

Six different acylthiourea ligands (L1–L6) and their corresponding Ru (II)-p-cymene
complexes (P1–P6) were designed to explore the structure–activity relationship of the …

Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …

Photodynamic therapy (PDT) is a treatment modality where light-mediated activation of
photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …

Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Lung cancer is one of the most common malignancies with the highest mortality rate and the
second-highest incidence rate after breast cancer, posing a serious threat to human health …

Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …