Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) is an inflammatory
condition of the upper airways. Optimal management is unclear. Objective We compared the …

With the increasing recognition of the role of type 2 immune responses in chronic
rhinosinusitis, its severity, recurrence, and comorbidities, several biologics targeting IL-4, IL …

Background Eosinophilic inflammation has been implicated in the pathogenesis, severity,
and treatment responsiveness of chronic rhinosinusitis with nasal polyps (CRSwNP) …

Background Chronic rhinosinusitis with nasal polyps is frequently managed with endoscopic
sinus surgery (ESS). Prior studies describe individual clinical variables and eosinophil …

Chronic rhinosinusitis (CRS) occurs in> 10% of the adult population in Europe and the USA
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …

Background Among patients with chronic rhinosinusitis with nasal polyps (CRSwNP),
randomized clinical trials (RCTs) of biologics, such as anti-interleukin-4/interleukin-13 …

Introduction: Compared with the placebo, biologics are beneficial in reducing nasal polyp
mass and safe in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). However …

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory
disease treated with sinus surgery when refractory to medical intervention. However …

Background Emerging evidence suggests that chronic rhinosinusitis with nasal polyps
(CRSwNP) is a highly heterogeneous disease with disparate inflammatory characteristics …

Abstract Purpose of Review Despite molecular underlying advances, limited and divergent
data on monoclonal antibodies (mAb) therapy in chronic rhinosinusitis with nasal polyps …