Inflammation plays a significant role in the occurrence and development of multiple
diseases. This study comprehensively reviews and presents literature from the last five …

Acupuncture is a centuried and unfading treatment of traditional Chinese medicine, which
has been proved to exert curative effects on various disorders. Numerous works have been …

Growing evidences show that gut microbiota is associated with the pathogenesis of
Parkinson's disease (PD) and the gut-brain axis can be promising target for the development …

Chronic pain reduces life quality and is an important clinical problem associated with
emotional and cognitive dysfunction. Epigenetic regulation of DNA methylation is involved in …

Pain can trigger central amplification called central sensitization, which ultimately results in
hyperalgesia and/or allodynia. Many reports have showed acupuncture has an analgesic …

Nociceptive signals are transmitted by peripheral afferents to the central nervous system
under pain condition, a process that involves various neurotransmitters and pathways …

Although electroacupuncture (EA) has become a worldwide practice, little is understood
about its precise target in the central nervous system (CNS) and the cell type-specific …

Acupuncture has been used to treat multiple medical conditions, but whether the diverse
effects of acupuncture are intrinsically linked and how they might be connected have yet to …

Depression is a serious psychiatric disorder with an enormous socioeconomic burden, and it
is commonly comorbid with pain, chronic fatigue, or other inflammatory diseases. Recent …

Objectives: Although the local response induced by acupuncture manipulation has been
considered to be among the important factors that induce the effects of acupuncture, this …