Amitriptyline or Not, That Is the Question: Pharmacogenetic Testing of CYP2D6 and CYP2C19 Identifies Patients with Low or High Risk for Side Effects in …
W Steimer, K Zopf, S von Amelunxen, H Pfeiffer… - Clinical …, 2005 - academic.oup.com
Background: Amitriptyline has been replaced in many countries by alternative and more
expensive drugs based on claims of improved tolerability and toxicity and despite slightly …
expensive drugs based on claims of improved tolerability and toxicity and despite slightly …
Toward an understanding of the protein interaction network of the human liver
Proteome‐scale protein interaction maps are available for many organisms, ranging from
bacteria, yeast, worms and flies to humans. These maps provide substantial new insights …
bacteria, yeast, worms and flies to humans. These maps provide substantial new insights …
[HTML][HTML] Pathway and network approaches for identification of cancer signature markers from omics data
J Wang, Y Zuo, Y Man, I Avital, A Stojadinovic… - Journal of …, 2015 - ncbi.nlm.nih.gov
The advancement of high throughput omic technologies during the past few years has made
it possible to perform many complex assays in a much shorter time than the traditional …
it possible to perform many complex assays in a much shorter time than the traditional …
Gene expression signature of human HepG2 cell line
S Costantini, G Di Bernardo, M Cammarota, G Castello… - Gene, 2013 - Elsevier
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and is
associated with various clinico-pathological characteristics such as genetic mutations and …
associated with various clinico-pathological characteristics such as genetic mutations and …
[HTML][HTML] Biomedical text mining and its applications
R Rodriguez-Esteban - PLoS computational biology, 2009 - journals.plos.org
This tutorial is intended for biologists and computational biologists interested in adding text
mining tools to their bioinformatics toolbox. As an illustrative example, the tutorial examines …
mining tools to their bioinformatics toolbox. As an illustrative example, the tutorial examines …
[HTML][HTML] Expression of nicotinamide N-methyltransferase in hepatocellular carcinoma is associated with poor prognosis
J Kim, SJ Hong, EK Lim, YS Yu, SW Kim… - Journal of Experimental …, 2009 - Springer
Background Hepatocellular carcinoma (HCC) is the most common tumor in the adult liver,
with high relapse and mortality rates despite diverse treatment modalities. In this study …
with high relapse and mortality rates despite diverse treatment modalities. In this study …
[HTML][HTML] Immune–related biomarkers shared by inflammatory bowel disease and liver cancer
It has been indicated that there is an association between inflammatory bowel disease (IBD)
and hepatocellular carcinoma (HCC). However, the molecular mechanism underlying the …
and hepatocellular carcinoma (HCC). However, the molecular mechanism underlying the …
HCVpro: hepatitis C virus protein interaction database
SK Kwofie, U Schaefer, VS Sundararajan… - Infection, Genetics and …, 2011 - Elsevier
It is essential to catalog characterized hepatitis C virus (HCV) protein–protein interaction
(PPI) data and the associated plethora of vital functional information to augment the search …
(PPI) data and the associated plethora of vital functional information to augment the search …
[HTML][HTML] Gene expression-based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor prognosis. Currently,
only sorafenib is approved by the FDA for advanced HCC treatment; therefore, there is an …
only sorafenib is approved by the FDA for advanced HCC treatment; therefore, there is an …
Micronome revealed miR-205-5p as key regulator of VEGFA during cancer related angiogenesis in hepatocellular carcinoma
The high ratio of global mortality rate to incidence rate and steep increase in incidence of
liver cancer warrants need for advancement of innovative cancer treatment and therapy for …
liver cancer warrants need for advancement of innovative cancer treatment and therapy for …