Differential metabolome in rheumatoid arthritis: a brief perspective

P Agnihotri, Monu, S Ramani, D Chakraborty… - Current Rheumatology …, 2021 - Springer
Abstract Purpose of Review Rheumatoid arthritis (RA) is a chronic autoimmune,
inflammatory disease of the synovium that affects the movable joints. It develops due to the …

Predicting diagnostic gene expression profiles associated with immune infiltration in patients with lupus nephritis

L Wang, Z Yang, H Yu, W Lin, R Wu, H Yang… - Frontiers in …, 2022 - frontiersin.org
Objective To identify potential diagnostic markers of lupus nephritis (LN) based on
bioinformatics and machine learning and to explore the significance of immune cell …

Tumor-derived CCL5 recruits cancer-associated fibroblasts and promotes tumor cell proliferation in esophageal squamous cell carcinoma

KJ Dunbar, TA Karakasheva, Q Tang, G Efe… - Molecular Cancer …, 2023 - AACR
Cancer-associated fibroblasts (CAF) can promote tumor growth, metastasis, and therapeutic
resistance in esophageal squamous cell carcinoma (ESCC), but the mechanisms of action …

Identification of an Immune‐Related Gene Signature Associated with Prognosis and Tumor Microenvironment in Esophageal Cancer

C Li, W Zhou, J Zhu, Q Shen, G Wang… - BioMed Research …, 2022 - Wiley Online Library
Background. Esophageal cancer (EC) is a common malignant tumor of the digestive system
with high mortality and morbidity. Current evidence suggests that immune cells and …

Hypermethylation-mediated lncRNA MAGI2-AS3 downregulation facilitates malignant progression of laryngeal squamous cell carcinoma via interacting with SPT6

J Wang, C Yang, H Cao, J Yang, W Meng… - Cell …, 2023 - journals.sagepub.com
Long noncoding RNAs (lncRNAs) have an effect on the occurrence and progression of a
considerable number of diseases, especially cancer. Existing research has suggested that …

Identification and validation of necroptosis-related prognostic gene signature and tumor immune microenvironment infiltration characterization in esophageal …

K Sun, J Hong, D Chen, Z Luo, J Li - BMC gastroenterology, 2022 - Springer
Background Esophageal carcinoma (ESCA) is a common malignancy with a poor prognosis.
Previous research has suggested that necroptosis is involved in anti-tumor immunity and …

Multi‐omics data identified TP53 and LRP1B as key regulatory gene related to immune phenotypes via EPCAM in HCC

L Shi, J Cao, X Lei, Y Shi, L Wu - Cancer Medicine, 2022 - Wiley Online Library
Background Many studies showed that the prognosis of hepatocellular carcinoma (HCC)
was significantly associated with the expressions of TP53 and LRP1B. However, the …

The cellular signaling and regulatory role of protein phosphatase in tumor diagnosis: Upstream miRNAs of PTEN

Y He, E Mingyan, S Liu, G Liu, Y Cao - International Journal of Biological …, 2024 - Elsevier
Protein phosphatases have demonstrated considerable promise in the realm of early tumor
diagnosis across various malignancies. These enzymes play a critical role in modulating the …

Immune infiltration represents potential diagnostic and prognostic biomarkers for esophageal squamous cell carcinoma

M Li, P Chen, Y Zhao, X Feng, S Gao… - BioMed Research …, 2022 - Wiley Online Library
Background. Immune infiltrates in the tumor microenvironment have established roles in
tumor growth, invasion, and metastasis. However, the diagnostic and prognostic potential of …

Mining of prognosis-related genes in cervical squamous cell carcinoma immune microenvironment

J Ma, P Cheng, X Chen, C Zhou, W Zheng - PeerJ, 2020 - peerj.com
Purpose The aim of this study was to explore the effective immune scoring method and mine
the novel and potential immune microenvironment-related diagnostic and prognostic …