CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy

K Pan, H Farrukh, VCSR Chittepu, H Xu, C Pan… - Journal of Experimental …, 2022 - Springer
Adoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made
tremendous progress with five CAR T therapies approved by the US Food and Drug …

[HTML][HTML] Multi-system inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection: review of clinical presentation, hypothetical pathogenesis, and …

NA Nakra, DA Blumberg, A Herrera-Guerra… - Children, 2020 - mdpi.com
Children | Free Full-Text | Multi-System Inflammatory Syndrome in Children (MIS-C)
Following SARS-CoV-2 Infection: Review of Clinical Presentation, Hypothetical …

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

B Liu, M Li, Z Zhou, X Guan, Y Xiang - Journal of autoimmunity, 2020 - Elsevier
The emergent outbreak of coronavirus disease 2019 (COVID-19) has caused a global
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are …

COVID-19: Immunology and treatment options

S Felsenstein, JA Herbert, PS McNamara… - Clinical …, 2020 - Elsevier
The novel coronavirus SARS-CoV2 causes COVID-19, a pandemic threatening millions. As
protective immunity does not exist in humans and the virus is capable of escaping innate …

The unique characteristics of COVID-19 coagulopathy

T Iba, JH Levy, JM Connors, TE Warkentin, J Thachil… - Critical care, 2020 - Springer
Thrombotic complications and coagulopathy frequently occur in COVID-19. However, the
characteristics of COVID-19-associated coagulopathy (CAC) are distinct from those seen …

Distinct clinical and immunological features of SARS–CoV-2–induced multisystem inflammatory syndrome in children

PY Lee, M Day-Lewis, LA Henderson… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Pediatric SARS–CoV-2 infection can be complicated by a dangerous
hyperinflammatory condition termed multisystem inflammatory syndrome in children (MIS-C) …

A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a national …

R Harwood, B Allin, CE Jones, E Whittaker… - The Lancet Child & …, 2021 - thelancet.com
Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-
TS) is a novel condition that was first reported in April, 2020. We aimed to develop a national …

Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience

C Bryce, Z Grimes, E Pujadas, S Ahuja, MB Beasley… - Modern …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical
syndrome COVID-19 are causing overwhelming morbidity and mortality around the globe …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in
the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …

Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort

M Pouletty, C Borocco, N Ouldali, M Caseris… - Annals of the …, 2020 - ard.bmj.com
Background Current data suggest that COVID-19 is less frequent in children, with a milder
course. However, over the past weeks, an increase in the number of children presenting to …