Hypoxic regulation of the fetal cerebral circulation
W Pearce - Journal of applied physiology, 2006 - journals.physiology.org
Fetal cerebrovascular responses to acute hypoxia are fundamentally different from those
observed in the adult cerebral circulation. The magnitude of hypoxic vasodilatation in the …
observed in the adult cerebral circulation. The magnitude of hypoxic vasodilatation in the …
Functions of serotonin in hypoxic pulmonary vascular remodeling
JM Esteve, JM Launay, O Kellermann… - Cell biochemistry and …, 2007 - Springer
In lung vasculature, reversible constriction of smooth muscle cells exists in response to
acute decrease in oxygen levels (hypoxia). Progressive and irreversible structural …
acute decrease in oxygen levels (hypoxia). Progressive and irreversible structural …
Executive summary of the workshop on oxygen in neonatal therapies: controversies and opportunities for research
RD Higgins, E Bancalari, M Willinger, TNK Raju - Pediatrics, 2007 - publications.aap.org
One of the most complex areas in perinatal/neonatal medicine is the use of oxygen in
neonatal therapies. To address the knowledge gaps that preclude optimal, evidence-based …
neonatal therapies. To address the knowledge gaps that preclude optimal, evidence-based …
Contribution of gene-modified mice and rats to our understanding of the cardiovascular pharmacology of serotonin
L Monassier, MA Laplante, T Ayadi, S Doly… - Pharmacology & …, 2010 - Elsevier
This review focuses on new insights provided by gene-modified animals into the
cardiovascular pharmacology of serotonin. During their development, mice mutant for …
cardiovascular pharmacology of serotonin. During their development, mice mutant for …
Chronic hypoxia attenuates the vasodilator efficacy of protein kinase G in fetal and adult ovine cerebral arteries
RB Thorpe, MC Hubbell… - American Journal …, 2017 - journals.physiology.org
Long-term hypoxia (LTH) attenuates nitric oxide-induced vasorelaxation in ovine middle
cerebral arteries. Because cGMP-dependent protein kinase (PKG) is an important mediator …
cerebral arteries. Because cGMP-dependent protein kinase (PKG) is an important mediator …
Hypoxia induces internalization of κ-opioid receptor
C Xi, X Liang, C Chen, H Babazada, T Li, R Liu - Anesthesiology, 2017 - pubs.asahq.org
Background It has been demonstrated that κ-opioid receptor agonists can reduce hypoxia–
ischemia brain injury in animal models. However, it is unclear how the κ-opioid receptor …
ischemia brain injury in animal models. However, it is unclear how the κ-opioid receptor …
Direct effects of acute hypoxia on the reactivity of peripheral arteries of the chicken embryo
K Ruijtenbeek, CGA Kessels… - American Journal …, 2002 - journals.physiology.org
In the chicken embryo, acute hypoxemia results in cardiovascular responses, including an
increased peripheral resistance. We investigated whether local direct effects of decreased …
increased peripheral resistance. We investigated whether local direct effects of decreased …
Maturation of intracellular calcium homeostasis in sheep pulmonary arterial smooth muscle cells
R Goyal, KD Creel, E Chavis… - … of Physiology-Lung …, 2008 - journals.physiology.org
Cytosolic Ca2+ signaling dynamics are important to pulmonary arterial reactivity, and
alterations are implicated in pulmonary vascular disorders. Yet, adaptations in cellular Ca2+ …
alterations are implicated in pulmonary vascular disorders. Yet, adaptations in cellular Ca2+ …
Postnatal maturation modulates relationships among cytosolic Ca2+, myosin light chain phosphorylation, and contractile tone in ovine cerebral arteries
RJ Sandoval, ER Injeti… - American Journal of …, 2007 - journals.physiology.org
The present study tests the hypothesis that age-related changes in patterns of agonist-
induced myofilament Ca2+ sensitization involve corresponding differences in the relative …
induced myofilament Ca2+ sensitization involve corresponding differences in the relative …
Maturation alters the contribution of potassium channels to resting and 5HT-induced tone in small cerebral arteries of the sheep
GQ Teng, SM Nauli, JE Brayden, WJ Pearce - Developmental brain …, 2002 - Elsevier
To address the hypothesis that maturation alters the contribution of K-channels to resting
and agonist-induced tone in small cerebral arteries, second branch middle cerebral arteries …
and agonist-induced tone in small cerebral arteries, second branch middle cerebral arteries …