[HTML][HTML] Targeted drug delivery via the use of ECM-mimetic materials

J Hwang, MO Sullivan, KL Kiick - Frontiers in Bioengineering and …, 2020 - frontiersin.org
The use of drug delivery vehicles to improve the efficacy of drugs and to target their action at
effective concentrations over desired periods of time has been an active topic of research …

Strategies to prevent surgical site infections in acute care hospitals: 2014 update

DJ Anderson, K Podgorny, SI Berríos-Torres… - Infection Control & …, 2014 - cambridge.org
Previously published guidelines are available that provide comprehensive
recommendations for detecting and preventing healthcare-associated infections (HAIs). The …

Strategies to prevent surgical site infections in acute-care hospitals: 2022 Update

MS Calderwood, DJ Anderson, DW Bratzler… - Infection Control & …, 2023 - cambridge.org
The intent of this document is to highlight practical recommendations in a concise format
designed to assist acute-care hospitals in implementing and prioritizing their surgical-site …

[HTML][HTML] Local application of gentamicin-containing collagen implant in the prophylaxis and treatment of surgical site infection in orthopaedic surgery

H Knaepler - International journal of surgery, 2012 - Elsevier
BACKGROUND: There is still significant risk of patients developing surgical site infection
(SSI) following orthopaedic surgery due to growing demand for joint surgery in high-risk …

Electro-microenvironment modulated inhibition of endogenous biofilms by piezo implants for ultrasound-localized intestinal perforation disinfection

X Zhao, LY Wang, CY Tang, K Li, YH Huang, YR Duan… - Biomaterials, 2023 - Elsevier
Endogenous bacterial infections from damaged gastrointestinal (GI) organs have high
potential to cause systemic inflammatory responses and life-threatening sepsis. Current …

Randomized clinical trial of intestinal ostomy takedown comparing pursestring wound closure vs conventional closure to eliminate the risk of wound infection

D Camacho-Mauries, JL Rodriguez-Díaz… - Diseases of the colon …, 2013 - journals.lww.com
BACKGROUND: The use of temporary stomas has been demonstrated to reduce septic
complications, especially in high-risk anastomosis; therefore, it is necessary to reduce the …

Topical antimicrobial prophylaxis in colorectal surgery for the prevention of surgical wound infection: a systematic review and meta-analysis

RL Nelson, A Kravets, R Khateeb, M Raza… - Techniques in …, 2018 - Springer
Background Among the techniques investigated to reduce the risk of surgical wound
infection or surgical space infection (SSI) in patients having colorectal surgery are topical …

Antimicrobial formulation and delivery in the prevention of surgical site infection

PB O'Neal, KMF Itani - Surgical infections, 2016 - liebertpub.com
Background: A number of adjunct antimicrobial measures have been studied in an attempt
to reduce surgical site infection (SSI) rates. In addition to parenteral antibiotic prophylaxis …

[HTML][HTML] Collagen-Based Biomaterial as Drug Delivery Module

AK Verma - Collagen Biomaterials, 2022 - intechopen.com
In the field of medicine, controlled drug delivery has become a major challenge due to
inefficiency of drug at critical parameters such as permeability, solubility, half-life, targeting …

Surgical site infections and their prevention

ML Schweizer, LA Herwaldt - Current opinion in infectious …, 2012 - journals.lww.com
There is some evidence that bundled interventions can reduce SSIs. However, more
research should be done evaluating the effectiveness of these interventions. Future studies …