This year marks the 20th anniversary of the discovery of leptin, which has tremendously
stimulated translational obesity research. The discovery of leptin has led to realizations that …

Objective The purpose of this work was to meta-analyze prospective studies that have
evaluated the effect of a Mediterranean diet on the development of type 2 diabetes …

Receptors of leptin, the prototypical adipokine, are expressed throughout the cortex and
several other areas of the brain. Although typically studied for its role in energy intake and …

Leptin, a peptide hormone secreted by adipocytes, plays a central role in controlling appetite
and weight in both rodents and humans. Basic science and clinical research suggest that …

The objective of this systematic review was to determine the current state of the literature
regarding how adipocytokines associate with mental health symptoms/disorders in youth …

Diabetes mellitus type 2 (DMT-2) presents with a growing incidence, and its complications
contribute mainly to cardiovascular disease and overall mortality. DMT-2 prevention and …

Leptin is a hormone secreted by adipocytes that regulates energy metabolism via peripheral
action on glucose synthesis and utilization as well as through central regulation of food …

Analytical and experimental studies confirm relationships between the consumption of
certain foods and cardiovascular disease, diabetes, and cancer. Mediterranean diet patterns …

Over the past several years, mitochondrial dysfunction has been linked to an increasing
number of human illnesses, making mitochondrial proteins (MPs) an ever more appealing …

Obesity is a major and rapidly growing global health concern and is known to be associated
with significant morbidity and mortality. The obese state, irrespective of complication, is …