The calcium-responsive molecule, calcineurin, has been well characterized to play a causal
role in pathological cardiac hypertrophy over the past decade. However, the intrinsic …

Background: Despite promising advances in stem cell-based therapy, the treatment of
ischemic cardiovascular diseases remains a big challenge due to both the insufficient in vivo …

Bradycardia arising from pacemaker dysfunction can be debilitating and life threatening.
Electronic pacemakers serve as effective treatment options for pacemaker dysfunction. They …

Optogenetics is an emerging, interdisciplinary research area which combines genetic and
optical technologies to steer and monitor specific biological processes. To this end, light …

Low uptake efficiency in vivo as well as systemic toxicities of nucleic‐acid nanovehicles
substantially retard the clinical translation of gene therapy. Targeted gene delivery to …

Cardiac transplantation is the gold standard treatment for end-stage heart failure. However,
it remains limited by the number of available donor hearts and complications such as …

Atrial fibrillation (AF) remains a complex and challenging arrhythmia to treat, necessitating
innovative therapeutic strategies. This review explores the evolving landscape of gene …

The detrimental impact of heavy metals on cardiovascular well-being is a global concern,
and engaging in suitable physical activity has been shown to confer cardiovascular …

During the past decade, calcium/calmodulin-dependent protein kinase II (CaMKII) has
emerged as a central culprit in the development of cardiac arrhythmia and heart failure. This …

Cytokine therapies have emerged during the past decade as promising noninvasive
treatments for heart disease. In general, current drug treatments are directed towards …