In vivo microdialysis was used to examine the effects of the noncompetitive NMDA receptor
antagonist dizocilpine maleate (MK-801) on basal and d-amphetamine (AMPH)-induced …

The basal ganglia and cortex work in concert to orchestrate and execute planned behaviors.
Historically, the basal ganglia are best known for their motor functions. This association was …

Parkinson's disease (PD) symptoms originate from the loss of the dopaminergic control of
neuronal activity in the striatum. Permanent loss of dopaminergic terminals in the striatum …

The role of striatal dopamine (DA) in mediating ischemic neuronal death was studied in the
rat. Two weeks after unilateral substantia nigra lesion, rats were subjected to 20 min of …

The present experiments were designed to further examine the hypothesis that receptor
subtype determines the direction of dopamine's (DA) ability to modulate neostriatal neuronal …

The chemical synapse is the principal form of contact between neurons of the central
nervous system. These synapses are typically configured as presynaptic axon terminations …

Various aspects of the distribution of catecholaminergic (CA) perikarya and fibers in the
avian brain have been described in previous studies. The earliest studies on this topic used …

The paraventricular nucleus of the thalamus (PVT) participates in the functional integration
of limbic cortical and striatal circuitry. In the rat, the PVT projects to the deep layers of the …

Although thalamic projections to the dorsal striatum are well described in primates and other
species, little is known about thalamic projections to the ventral or “limbic” striatum in the …

Brain microdialysis has become a frequently used method to study the extracellular
concentrations of neurotransmitters in specific areas of the brain. For years, and this is still …